نتایج جستجو برای: young gerbil

تعداد نتایج: 247025  

Journal: :Acta medica Okayama 2001
M A Bagum O Miyamoto T Toyoshima T Masada S Nagahata T Itano

The implication of low affinity nerve growth factor receptor (p75NGFR), which is believed to play a pro-apoptotic role, in delayed neuronal death (DND) after ischemia in the gerbil hippocampus was investigated. Immunohistochemistry and Western blot analysis revealed that the presence of p75 NGFR immunoreactivity (IR) was negligible in the hippocampus of the sham control gerbil but appeared clea...

Journal: :Stroke 1988
T Sasaki T Nakagomi T Kirino A Tamura M Noguchi I Saito K Takakura

The purpose of our experiment was to examine whether the cyclooxygenase inhibitor indomethacin ameliorates neuronal injury in the gerbil hippocampal CA1 sector following 5 minutes of forebrain ischemia. Thirty minutes before bilateral carotid artery occlusion, Mongolian gerbils were injected intraperitoneally with 1 (n = 10), 2 (n = 10), 5 (n = 12), or 10 (n = 7) mg/kg of indomethacin. Seven da...

2005
Tomio Sasaki Tadayoshi Nakagomi Takaaki Kirino Akira Tamura Kintomo Takakura

The purpose of our experiment was to examine whether the cyclooxygenase inhibitor indomethacin ameliorates neuronal injury in the gerbil hippocampal CA, sector following 5 minutes of forebrain ischemia. Thirty minutes before bilateral carotid artery occlusion, Mongolian gerbils were injected intraperitoneally with 1 (n = 10), 2 (n = 10), S (n = 12), or 10 (n = 7) mg/kg of indomethacin. Seven da...

2013
Eun Hee Ahn Dae Won Kim Min Jea Shin Hyo Sang Jo Seon Ae Eom Duk-Soo Kim Eun Young Park Jong Hoon Park Sung-Woo Cho Jinseu Park Won Sik Eum Ora Son Hyun Sook Hwang Soo Young Choi

We examined the ways in which fenobam could promote not only the transduction of PEP-1-FK506BP into cells and tissues but also the neuroprotective effect of PEP-1-FK506BP against ischemic damage. Fenobam strongly enhanced the protective effect of PEP-1-FK506BP against H2O2-induced toxicity and DNA fragmentation in C6 cells. In addition, combinational treatment of fenobam with PEP-1-FK506BP sign...

Journal: : 2023

The study is the first attempt to generalize data on burrow biocenoses of great gerbil (Rhombomys opimus (Lichtenstein, 1823)) in region persistent plague epizootics lowland part Karakum Desert (Southern Turkmenistan). material was collected May, November, and December 1987–1988 using trapping cylinders residential non-residential colonies gerbil. Coleoptera made up about 40% species compositio...

2015
Susanne Radtke-Schuller Sabine Seeler Benedikt Grothe

Degeneration of hearing and vertigo are symptoms of age-related auditory and vestibular disorders reflecting multifactorial changes in the peripheral and central nervous system whose interplay remains largely unknown. Originating bilaterally in the brain stem, vestibular and auditory efferent cholinergic projections exert feedback control on the peripheral sensory organs, and modulate sensory p...

Journal: :Current neurovascular research 2005
David T Laidley Frederick Colbourne Dale Corbett

The Mongolian gerbil (Meriones unguiculatus) has been used extensively as a model of forebrain ischemia. Its unique susceptibility to ischemia was suggested to be due to an incomplete circle of Willis. The relative ease to which ischemia can be induced combined with highly reproducible delayed CA1 cell death following a 5 min occlusion made the model popular in neuroprotection studies. Presentl...

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