The present studies were performed to further characterize a mouse yolk sac protein which is similar or identical to the vitamin D-dependent intestinal calcium-binding protein (CaBP). Yolk sac protein and purified rat intestinal CaBP displayed full identity upon immunodiffusion (Ouchterlony) using antiserum to the rat intestinal CaBP. Immunoreactive CaBP in yolk sac homogenates eluted from gel ...

OBJECTIVE To review the process of blood-cell formation in the murine and human yolk sac. DATA SOURCES Most articles were selected from the PubMed database. DATA SYNTHESIS The yolk sac is the first site of blood-cell production during murine and human ontogeny. Primitive erythroid cells originate in the yolk sac and complete their maturation, including enucleation, in the bloodstream. Thoug...

Primary hepatic yolk sac tumor is a rare extra-gonadal germ cell tumor in children and adults. Two important differential diagnoses for hepatic tumor in a pediatric patient are hepatocellular carcinoma and hepatoblastoma. A 22-month-old boy presented to our hospital with acute respiratory distress and increased serum alphafetoprotein. His symptom was caused by a ruptured massive intraabdominal ...

INTRODUCTION Yolk sac tumors represent only 5%-7% of intracranial germ cell tumors, which comprise about 1% of all primary brain tumors in adults. Literature data about nonspecific imaging characteristics of these tumors are scant. We presented magnetic resonance imaging findings with diffusion-weighted imaging and proton magnetic resonance spectroscopy of this rare type of tumor in an adult pa...

The possible relationship among malignancy, differentiation, and chro mosomal constitution of primary embryo-derived tumors was studied. Tumors were induced by transplanting 7-day-oId mouse embryos under the kidney capsule of syngeneic BALB/c recipients. Transplantation of 101 embryos resulted in 81 tumor-bearing mice: 36 teratocarcinomas; 18 teratomas; and 27 yolk sac tumors. Some of the yolk ...

Address for Correspondence: Dr. Geetanjali Srivastava, Junior resident IIIrd year,Department of Anatomy, Era’s Lucknow medical college, Lucknow-226003, Uttar Pradesh, India. 9792171135, E-Mail: [email protected] Introduction: The yolk sac is the first extra embryonic structure that becomes sonographically visible within the gestational sac and acts as the primary route of excha...

The mechanisms involved in the induction of yolk sac mesoderm into blood islands and the role of visceral endoderm and mesoderm cells in regulating the restricted differentiation and proliferation of hematopoietic cells in the yolk sac remain largely unexplored. To better define the role of murine yolk sac microenvironment cells in supporting hematopoiesis, we established cell lines from day-9....

Background: Bilateral synchronous testis germ cell tumors with different histopathology are not common. Case Presentation: Here, a case of 27-year-old male who is reported presented with bilateral testicular swellings. There was a high α-fetoprotein level with bilateral lesions on scrotal USG. Bilateral orchiectomy was performed. According to pathology report, there was a right testicular semi...

In order to evaluate the hypothetical activity of foetal hepatic factors on putative yolk-sac haemopoietic stem cells we used the Double Diffusion Chamber (DDC) techniqUe. The DDC were made of a regulator compartment, where foetal hepatic tissue was introduced and a test compartment where visceral yolk-sac cells were cultured. In this system a hepatic signal induced the yolk-sac stem cells to d...

Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a conditional knock-out (cKO) strategy was used to delete YY1 from the visceral endoderm of the yolk sac and the definitive endoderm of the embryo. cKO embryos display profound yolk sac defects at 9.5 days post coitum (dpc), including disrupte...