Quantifying the future health burden attributed to fine particulate matter (PM2.5) and ozone (O3) in China is challenging when jointly accounting for emissions, climate, population changes. Future burdens caused by PM2.5 O3 remain largely understudied. In this study, Goddard Earth Observing System chemical transport model (GEOS-Chem) was used calculate concentrations from 2010 2050 under four R...

3 Chen Zhang, Chek Kun Tan, Craig McFarlane, Mridula Sharma, Nguan Soon Tan*, Ravi 4 Kambadur,*# 5 1. School of Biological Sciences, Nanyang Technological University, Singapore 637551. 6 2 Singapore Institute for Clinical Sciences, A*STAR, 30 Medical Centre Drive, National 7 University of Singapore, Singapore 8 3 Department of Biochemistry, YLL School of Medicine, National University of 9 Singa...

Background & Aims: Breast cancer is the second most common cancer in women, with the peak frequency of a decade lower than the global age. The aim of this cross sectional study is to estimate the burden of breast cancer in women in Western Azerbaijan Province in 2013. Materials & Methods:  In this cross-sectional study, the information needed to calculate YLD and YLL creating the total DA...

OBJECTIVE To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness analysis, comparing the efficiency of an eflornithine-based approach with melarsoprol. Endpoints calculated were: cost per death avoided; incremen...

Tobacco use is a well-established risk factor for many types of cancers. Recent data on selected cancer incidence and mortality related to smoking in the Indonesian population are provided in this study. Morbidity and mortality data were derived from GLOBOCAN 2012 and the population attributable fraction (PAF) was estimated using the standard methodology developed by the World Health Organizati...

BACKGROUND Ideally, the allocation of research funding for each specific type of cancer should be proportional to its societal burden. This burden can be estimated with the metric 'years of life lost' (YLL), which combines overall mortality and age at death. METHODS Using United Kingdom data from 2010, we compared research funding from the National Cancer Research Institute to this YLL burden...

Introduction: Mental and substance use disorders (MD) are highly prevalent and have a high social and economic cost. Objective: To describe the burden of disease attributable to mental and substance use disorders in Brazil and Federated Units in 1990 and 2015. Methods: Descriptive study of the burden of mental and substance use disorders, using age-standardized estimates from the Global Bur...

BACKGROUND Laboratory-confirmed deaths grossly underestimate influenza mortality burden, so that reliable burden estimates are derived from indirect statistical studies, which are scarce in low- and middle-income settings. OBJECTIVES Here, we used statistical excess mortality models to estimate the burden of seasonal and pandemic influenza in China. METHODS We modeled data from a nationally...