In this research, the selective flotation of galena and sphalerite minerals was evaluated from a pyrite-rich lead-zinc sample. An optimum mixture of selective collectors against pyrite and also organic/inorganic pyrite depressants was obtained in the flotation of galena and sphalerite by an experimental mixture design. The effect of different collectors and pH values were investigated in the ob...

A short sequential synthesis of pyrrolidino- pyridines and pyrimidines illustrates the potential of combining Ugi-Smiles couplings with radical tin-free processes.

Some inhibitory agents against CYP2B6 have been reported, but none of these has been extensively characterized or compared with others, as to the potency and selectivity of inhibition toward CYP2B6. The goal of this work was to find a selective and potent chemical in vitro inhibitor toward CYP2B6 using bupropion hydroxylation as a model reaction. At the initial screening of more than 30 substan...

Pyridoazepinones are potentially interesting structures, yet they still underexploited in the medicinal chemistry field and hard to obtain synthetically. We present a general flexible synthetic route substituted pyridoazepinones, enabled by xanthate addition–transfer process, which furnishes target molecules from readily available starting materials generally good yields. The method shows funct...