Surgical site infections are common following surgical procedures, despite aseptic technique and prophylactic antibiotic use. Although gut commensals believed to limit certain in the intestine, an analogous role for skin has not been described. To identify bacteria with potential protect against infection, we characterized wound microbiome 52 patients who underwent cancer surgery healed without...

Introduction: Battlefield wounds are frequently contaminated with pathogenic microorganisms present on uniforms and skin. Although the development of serious infections can often be prevented by antibiotics, the rise in worldwide incidence of multiply antibiotic-resistant bacteria necessitates the discovery of alternative methods. In addition, traumatic wounds and burns may contain non-perfused...

INTRODUCTION Emergency department manages several kinds of wounds including simple, non-bite traumatic wounds and lacerations. Prophylactic antibiotic therapy is one of pre-scribed treatment in these conditions. We aimed to compare the clinical efficacy of the two day regimen of prophylactic antimicrobial agents with the five day regimen in simple traumatic but highly contaminated wounds. MET...

Delayed wound healing due to infection is a burden on healthcare systems, and the patient and caregiver alike. An emerging factor in infection and delayed healing is the presence development of biofilm in wounds. Biofilm is communities of microorganisms, protected by an extracellular matrix of slime in the wound, which can tolerate host defences and applied antimicrobials such as antibiotics or...

Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, systemic antibiotic therapy is required in case ...

Objective: We have provided evidence based critical review of the “Triangle of wound assessment made easy”. Background: Wound assessment is a vital step in managing patients with acute and chronic wounds in daily clinical practice. The natural progression of most wounds is to heal naturally in a coherent and timely manner, although a minority of wounds will fail to heal. The aim of treating rec...

Infection is the likeliest single cause of delayed healing in healing of chronic open wounds by secondary intention. If neglected it can progress from contamination to colonization and local infection through to systemic infection, sepsis and multiple organ dysfunction syndrome, and it can be life-threatening. Infection in chronic wounds is not as easy to define as in acute wounds, and is compl...

Background: The management of skin and soft tissue infections is a tedious job to tackle as many factors play important roles in wound healing. Wounds can be better managed healed faster if infection removed the way eliminate by use antiseptics, antibiotics solutions over wounds along with systemic antibiotics. In this study, we used cadexomer iodine ointment for various types wounds. Methods: ...