In the era of precision medicine, the impact of personalized dosing of busulfan is not clear. We undertook a retrospective analysis of 78 patients with myeloid malignancies who received fludarabine and busulfan (FluBu4) with or without measuring Bu pharmacokinetics (Bu PK) and those who received busulfan with cyclophosphamide (BuCy). Fifty-five patients received FluBu4, of whom 21 had Bu PK mea...

Acetylcholine and dopamine are neurotransmitters that play multiple important roles in perception and cognition. Pharmacological cholinergic enhancement reduces excitatory receptive field size of neurons in marmoset primary visual cortex and sharpens the spatial tuning of visual perception and visual cortical fMRI responses in humans. Moreover, previous studies show that manipulation of choline...

Intrusion detection systems continue to be a promising security technology. The arguably biggest problem with today’s intrusion detection systems is the sheer number of alerts they produce for events that are regarded as benign or non-critical by system administrators. A plethora of more and less complex solutions has been proposed to filter the relevant (i.e., correct) alerts that signature ba...

Hospital-acquired infections pose a significant risk to patient health, while their surveillance is an additional workload for hospital staff. Our overall aim is to build a surveillance system that reliably detects all patient records that potentially include hospital-acquired infections. This is to reduce the burden of having the hospital staff manually check patient records. This study focuse...

We will in this paper present an evaluation of how much stemming improves precision in information retrieval for Swedish texts. To perform this, we built an information retrieval tool with optional stemming and created a tagged corpus in Swedish. We know that stemming in information retrieval for English, Dutch and Slovenian gives better precision the more inflecting the language is, but precis...

introduction: today, production of organic farming and gardening is rising. the use of organic fertilizers such as animal manure has a long history. in recent years, the use of fertilizers and manure for providing the nutritional needs of plants, improve soil physical and chemical structure and reduce the environmental issues have been observed. animal manures can increase soil organic matter a...

to study the effect of different harvesting intensity on forage production of bromus tomentellus was considered of majid abad qorveh. treatments included four harvested intensity 25, 50 and 75 percent and control (no harvest).data were analyzed based on splitplot over time during four years(1386-1389) using sas and irristat software. the results showed that the main effect of year, different ha...

arcinorna of the esophagus comprises 2 percent of all malignant tumors and 10 percent of all esophagogastrointestinal tumors. The national figures in Table 1' point out the magnitude of the problem. The treatment of this condition is palliative in some 75 percent of the cases, since at diagnosis 75 percent of the cases have regional or distant nodal metastases. In untreated patients, 75 percent...