This research was purposely to study and determine the physicochemical characteristics, sensory hypocholesterolemic effects of purple sweet potato bread made from flour, starch, fiber-rich flour starch processing waste on white male species Wistar rats conducted in vivo. used a non-factorial randomized block design model with treatment 100% standard feed, 25% mixture bread, combination 50% heal...

We have recently demonstrated that in large arteries of spontaneously hypertensive rats (SHR), there is no increase of stiffness despite the increase in wall thickness, a sign of mechanical adaptation of the arterial wall to the higher level of stress. Because the dense plaques of smooth muscle are a major site of anchorage between the muscle cells and extracellular matrix, we determined by ele...

Background data during the gestation period were obtained from 128 Wistar Hannover GALAS rats and 26 Crl:CD(SD) pregnant rats in the control groups of our previous toxicity studies. The body weights of dams in the Wistar Hannover GALAS rats were significantly lower throughout the gestation period than those in the Crl:CD(SD) rats. In contrast, the time-dependent change in the body weight gain (...

The superior colliculus (SC), substantia nigra pars reticulata (SNPr), and striatum have been characterized as important structures involved in the modulation of seizure activity. In the current study, bicuculline (GABA(A) antagonist) and muscimol (GABA(A) agonist) were microinjected into the deep layers of either the anterior SC (aSC) or posterior SC (pSC) of genetically developed Wistar audio...

BACKGROUND Type 2 diabetes has become the single most frequent cause of end-stage renal disease. The Goto-Kakizaki rat is currently used as a model for lean type 2 diabetes, but its renal changes have not been fully characterized. We investigated long-term functional and structural renal changes in the Goto-Kakizaki rat to evaluate if this animal model resembles the changes observed in human di...

Aim: The current study investigated the anti-oxidant effects of vitamins on lead-induced reproductive toxicity in male wistar rats.
 Study Design: A total 48 Wistar rats divided into 6 groups 8 per group were used this study. Group 1 served as positive control and was given normal animal feed water ad libitum. 2 negative administered 10mg/kg body weight lead acetate (Pb) only, 3 with 200mg...

This study was conducted to investigate the mitigation of dietary aflatoxin in Wistar rats using extract from selected phyto-antioxidant sources. A total one hundred and twenty weighing between 180-190g (80 females 40 males) at six weeks old were allotted eight treatments with 15 per treatment (10 5 males), a completely randomized design. The Treatment 1 (Normal diet + no aflatoxin), 2 (Aflatox...

Spontaneous chloroleukemia occurred in three adult members of a colony of Wistar rats. The chloroleukemia from one of these rats has been maintained in random-bred Wistar rats by inoculating tumor cells from leukemic donors into suckling rats. This report describes the course and manifestations, hematology, and pathologic changes of this transplantable chloroleukemia through ten serial subtrans...