In Nature, there exist a variety of cardiovascular circulation networks in which the energetic ventricular load has both steady and pulsatile components. Steady load is related to the mean cardiac output (CO) and the haemodynamic resistance of the peripheral vascular system. On the other hand, the pulsatile load is determined by the simultaneous pressure and flow waveforms at the ventricular ou...

For a given cardiac function, the cyclic blood pressure (BP) curve results from 2 different phenotypes: the mean arterial pressure (MAP), a steady component reflecting the resistance of the microvascular network, and pulse pressure (PP), another component corresponding to large artery stiffness and wave reflections. Around birth, cardiovascular (CV) survival is critically influenced by the coup...

tients with neurotrauma. ANESTHESIOLOGY 2002; 96:595–9 21. Pfitzner J: Poiseuille and his law. Anaesthesia 1976; 31:273–5 22. Wang JJ, Flewitt JA, Shrive NG, Parker KH, Tyberg JV: Systemic venous circulation. Waves propagating on a windkessel: Relation of arterial and venous windkessel to systemic vascular resistance. Am J Physiol Heart Circ Physiol 2006; 290:H154–62 23. De Piccoli B, Rigo F, R...

The aorta, as the major conduit artery of the human body, is primarily thought of as a blood vessel that provides a low-resistance path for blood flow directed from the heart to peripheral organs and tissues. However, the aorta has another central hemodynamic function, whereby the elastic nature of the aortic wall provides a significant biomechanical buffering capacity complementing the pulsati...

Inlet and outlet boundary conditions (BCs) play an important role in newly emerged image-based computational hemodynamics for blood flows human arteries anatomically extracted from medical images. We developed physiological inlet BCs based on patients’ data integrated them into the volumetric lattice Boltzmann method. The BC is a pulsatile paraboloidal velocity profile, which fits real arterial...

Human blood pressure (BP) and its pulse wave has always been a popular topic since it’s bound up with the heart related risks. In this paper, we mainly focus on of brachial artery which is also widely used in measurement BP, hence constructed artery-based system by using multi-Windkessel model managed to generate reliable signal adjustable authentic human parameters. On basis, filtering techniq...

In the resonance theory, the radial dilatation is emphasized, and the blood pressure wave is transmitted in the form of “moving windkessel”. Based on this conjecture, we developed a semi-empirical procedure to describe the pressure distribution in a complex simulated model composed of a main tube and attached organs. Now we try to apply this fitting method to hemodynamics in vivo, and we tested...