The 20-year, U.S. $4 billion-dollar international effort to eradicate wild polioviruses now includes monovalent oral poliovirus type 1 vaccine (mOPV1), which was first given to 40 million children in India in April 2005. As this vaccine is being introduced to eliminate some of the last poliovirus reservoirs, the Global Polio Eradication Initiative is planning for the eventual synchronized world...

The National Poliovirus Reference Laboratory at the Victorian Infectious Diseases Reference Laboratory (VIDRL) is responsible for poliovirus testing for Australia and the Pacific Island countries. It is also a regional reference laboratory for the Western Pacific Region of the World Health Organization. Surveillance for acute flaccid paralysis, a clinical manifestation of poliomyelitis, is coor...

The poliovirus was declared extinct in 1988. In Morocco, the most recent case of wild (WPV) reported 1989. From 1994 to 2018, Kenitra's polio topographical and etiological epidemiology were described using WHO-recommended surveillance criteria. This retrospective descriptive study conducted following WHO guidelines examine topographic factors that contribute acute flaccid paralysis (AFP) Kénitr...

Pakistan is one of the two endemic countries for polio, reporting co-circulation WPV1 and cVDPV2. classified by International Health Regulations (IHR) as a state infected with Wild Poliovirus type 1 (WPV1) circulating Vaccine derived poliovirus 2 (cVDPV2) potential risk international spread. We describe an ongoing outbreak in North Waziristan district southern Khyber Pakhtunkhwa (KP) province l...

Two obstacles — the laboratory containment of wild-type poliovirus and uncertainties about the threat posed by vaccine-derived poliovirus (VDPV) — still stand in the pathway towards the final eradication of poliovirus. Both issues have generated considerable controversy. Dowdle et al. have proposed a systematic and logical approach to the containment of wild-type poliovirus, which needs to be c...

1498 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 11, No. 9, September 2005 in the neutralization and blocking ELISA assays, mostly because of SLEV. Complete test results from these horses, as well as from Colombian cattle and chickens, will be presented elsewhere. These serologic data should be considered indirect evidence of WNV activity in Colombia. We encourage Colombian human and ...