The investigation of phenotypes in model organisms has the potential to reveal the molecular mechanisms underlying disease. The large-scale comparative analysis of phenotypes across species can reveal novel associations between genotypes and diseases. We use the PhenomeNET network of phenotypic similarity to suggest genotype-disease association, combine them with drug-gene associations availabl...

The generalized likelihood ratio (GLR) statistic (Fan, Zhang, and Zhang (2001)) offered a generally applicable method for testing nonparametric hypotheses about nonparametric functions, but its efficiency is adversely affected by outlying observations and heavy-tailed distributions. Here a robust testing procedure is developed under the framework of the GLR by incorporating a Wilcoxon-type arti...

Objective: The experience of stuttering is more complex than its observable behaviors, and in order for a person who stutters (PWS) to truly experience fluent speech the complete experience of stuttering must be removed. This study investigates the effects of various speaking conditions on one aspect of the experience of stutteringanticipation of stuttering. Methods: Ten adult stutterers were a...

We consider the decision problem of making causal conclusions from observational data. Typically, using standard matched pairs techniques, there is a source of uncertainty that is not usually quantified, namely the uncertainty due to the choice of the experimenter: two different reasonable experimenters can easily have opposite results. In this work we present an alternative to the standard non...

The rank statistics Sn(t) = 1 n ∑n i=1 ciRi(t) (t ∈ R), with Ri(t) being the rank of ei−txi, i = 1, . . . , n and e1, . . . , en being the random sample from the basic distribution with the cdf F , are considered as a random process with t in the role of parameter. Under some assumptions on ci, xi and on the underlying distribution, it is proved that the process {Sn( t √n)− Sn(0)− ESn(t), |t|2 ...

Pertumbuhan dan perkembangan merupakan masalah utama yang terjadi pada anak, orang tua harus tau serta paham terkait pertumbuhan guna untuk mencegah gangguan tumbuh kembang banyak anak di Indonesia mengalami perkembangan. Peneliti ini memfokuskan pengetahuan mengenai usia 0-23 Bulan. Mengetahui Pengaruh Media E-Booklet Terhadap Pengetahuan Orang Tua Dalam Persiapan Perumbuhan Perkembangan Pada ...

The Wilcoxon Signed Rank test is typically called upon when testing whether a symmetric distribution has a specified centre and the Gaussianity is in question. As with all insurance policies it comes with a cost, even if small, in terms of power versus a t-test, when the distribution is indeed Gaussian. In this note we further show that even when the distribution tested is Gaussian there need n...

This study aims to examine the effect of Respect for Diversity Education Program on primary school students’ respect diversity and empathic tendency. The research design this is quasi-experimental, with 3x3 pre-tests, post-tests, follow-up tests, experimental, control, placebo groups. In study, Scale Ka-Si Empathic Tendency were used. was conducted a total 24 third-grade students selected exper...

i ABSTRACT Robust and stable decoding of neural signals is imperative for implementing a useful neuroprosthesis capable of carrying out dexterous tasks. A nonhuman primate (NHP) was trained to perform combined flexions of the thumb, index and middle fingers in addition to individual flexions and extensions of the same digits. An array of microelectrodes was implanted in the hand area of the mot...

‎in this paper‎, ‎we define the common minimal dominating signed‎ ‎graph of a given signed graph and offer a structural‎ ‎characterization of common minimal dominating signed graphs‎. ‎in‎ ‎the sequel‎, ‎we also obtained switching equivalence‎ ‎characterizations‎: ‎$overline{s} sim cmd(s)$ and $cmd(s) sim‎ ‎n(s)$‎, ‎where $overline{s}$‎, ‎$cmd(s)$ and $n(s)$ are complementary‎ ‎signed gra...