Enteric fever still remains a cause of significant morbidity and mortality, particularly in children. In countries with poor resources and inadequate access to basic health care system, like ours, where widespread antibiotic availability and prescribing leads to low sensitivity of blood cultures and where bone marrow cultures are difficult to perform, early detection of suggestive clinical feat...

BACKGROUND/AIMS The serodiagnosis of infection with Salmonella typhi, using the Widal agglutination assay, relies on patients' antibodies to the O = 9,12 lipopolysaccharide (LPS) antigens, H = d flagellar antigens, and the Vi capsular antigens. A Vi agglutination titre of > 1/40 has traditionally been regarded as indicative of recent infection with S typhi. In this study, 91 sera were used to a...

was performed at head-quarters on Ross Island, which only confirmed the diagnosis, and the value of this simple atropine test. A synopsis of a few cases may be of interest and these I briefly append below:? Case No. 1.?March 1924. Female aged 28. Vomiting, purging, severe vertigo, enlarged spleen and liver. Blood swarming with double malaria infection. Quinine injections intravenously did not c...

AIM To determine clinical, and therapeutic characteristics, and antibiotic susceptibility test results for typhoid fever. METHODS A retrospective study using data from medical records of all typhoid fever subjects which is confirmed by blood culture positive for S. typhi or S. paratyphi. This study was performed to determine clinical, laboratory, and therapeutic characteristics. Statistical a...

In spite of the constant reiteration in almost every publication on typhoid fever that bacteriological examination of the blood is the diagnostic method of choice in the early stage of the disease, coupled with the steady stream of post-war publications emphasizing the uselessness of the Widal test at this time, it is remarkable how many requests for the latter are still made as the primary tes...