Patients 18 mothers (mean age 25 y, 72% black) of preschool children (mean age 44 mo, 61% girls) were enrolled in a nutrition clinic for women and their children living in low income households. 12 of the mothers (67%) were obese (body mass index [BMI] >30 kg/m, 4 were overweight (BMI >25 kg/m), and 2 were neither overweight nor obese. All of the children had a weight for height percentile (WHP...

Renal cell carcinoma (RCC) is one of the most common urinary malignancies with a high rate of morbidity. MicroRNAs (miRNAs) have been shown to be critical post‑transcriptional regulators in tumorigenesis. The present study aimed to investigate the effect of miRNA (miR)‑539 on the proliferation and apoptosis of RCC. The expression of miR‑539 and high mobility group AT‑hook 2(HMGA2) were examined...

OBJECTIVE We have previously shown that racial composition of behavioral intervention groups does not affect achieved weight loss. However, it is unclear if the race of the interventionist affects intervention outcomes. The objective of this analysis is to estimate the impact of race concordance between participant and interventionist on weight change in the initial weight loss phase (phase I) ...

Abstract Introduction Treatment with sodium oxybate (SXB) has been associated weight loss in patients narcolepsy. Lower-sodium (LXB) contains the same active moiety as SXB, 92% less sodium, and is approved US for treatment of cataplexy or excessive daytime sleepiness ≥7 years age narcolepsy adults idiopathic hypersomnia. This analysis assessed changes after 14 weeks open-label LXB a phase 3 cli...

IMPORTANCE Few weight loss treatments produce clinically meaningful weight loss outcomes among black women, particularly in the primary care setting. New weight management strategies are necessary for this population. Weight gain prevention might be an effective treatment option, with particular benefits for overweight and class 1 obese black women. OBJECTIVE To compare changes in weight and ...

OBJECTIVE To investigate the short- and long-term effectiveness and the predictors of weight loss in a mobile phone weight-loss programme among healthy overweight adults. DESIGN One hundred and twenty-five healthy, overweight (BMI = 26-36 kg/m2), 25-44-year-old, screened volunteers were randomized to an experimental group (n 62) to use a mobile phone-operated weight-loss programme or to a con...

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The variability of mercury (Hg) levels in Swedish freshwater fish during almost 50 years was assessed based on a compilation of 44 927 observations from 2881 waters. To obtain comparable values, individual Hg concentrations of fish from any species and of any size were normalized to correspond to a standard 1-kg pike [median: 0.69 mg kg⁻¹ wet weight (ww), mean ± SD: 0.84 ± 0.67 mg kg⁻¹ ww]. The...