This historical review traces the con­ cept of work throughout the develop­ ment of occupational therapy. Para­ digm shifting is used as a framework for describing the conceptual defini­ tions and therapeutic uses of work in four developmental stages. T he concept of work is funda­ mental to our profession; the terms occupation and therapy con­ note the strong relationship be­ tween healing and...

T he field of neurotrophin biology has made great advances in recent years to include a greater understanding of signaling pathways and broader understanding of the diverse biological roles of these molecules. This review will focus primarily on the nerve growth factor family of neurotrophins and how recent descriptions of the molecular function of both the ligands and the receptors have helped...

number of new drugs which have appeared during the last three years have been included and the author has been very wise in exercising a judicious caution in their selection. The sulphanilamide group of drugs which, is still in an experimental stage has received adequate attention. The book has been well written and brings out with great clarity the really important actions and therapeutic uses...

Animal venoms have been used for therapeutic purposes since the dawn of recorded history. Only a small fraction, however, have been tested for pharmaceutical utility. Modern computational methods enable the systematic exploration of novel therapeutic uses for venom compounds. Unfortunately, there is currently no comprehensive resource describing the clinical effects of venoms to support this co...

mprovement of N2 fixation might be an effective strategy in peanut breeding for high yield under drought stress conditions. However, under water limited conditions peanut varieties having high water-use efficiency (WUE) are favorable. A pot experiment was conducted under greenhouse conditions at Khon Kaen University, Thailand during December 2002 to May 2003, and repeated during June 2003 t...

Fresh water supply and its security encounter a high level of fluctuating variability under global climate changes. To address these concerns in catchment water management, a good understanding of land use/cover impacts on the hydrological cycle affecting water supply is crucial. The objective of this study is to define a model to investigate the impact of existing land use/cover on water yield...

Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...