Cancer cachexia is a wasting condition, driven by systemic inflammation and oxidative stress. This study investigated eicosapentaenoic acid (EPA) in combination with oxypurinol as a treatment in a mouse model of cancer cachexia. Mice with cancer cachexia were randomized into 4 treatment groups (EPA (0.4 g/kg/day), oxypurinol (1 mmol/L ad-lib), combination, or control), and euthanized after 29 d...

Air quality models, such as the Community Multiscale Air Quality (CMAQ) model, indicate decidedly higher ozone near the surface of large interior water bodies, such as the Great Lakes and Chesapeake Bay. In order to test the validity of the model output, we performed surface measurements of ozone (O3) and total reactive nitrogen (NOy) on the 26-m Delaware II NOAA Small Research Vessel experimen...

 The effects of seasons on lipid and fatty acid profiles of muscle types (mantle and arm) of Mediterranean octopuses (common octopus-Octopus vulgaris and musky octopus-Eledone moschata) were investigated. The results showed that lipid levels ranged from 0.75% to 1.60% in both muscle types of octopuses which were considered as lean. Lipid levels in mantle tissues of both octopus species w...

Several studies have demonstrated that oral intake of n-3 polyunsaturated fatty acids, specifically eicosapentaenoic acid (EPA), prevents ventricular tachyarrhythmias (VT) with ischemic heart disease, but the underlying mechanisms still remain unclear. Thus, we examined the relation between the serum EPA/arachidonic acid (AA) ratio and electrophysiological properties in patients with ischemic h...

 The effects of seasons on lipid and fatty acid profiles of muscle types (mantle and arm) of Mediterranean octopuses (common octopus-Octopus vulgaris and musky octopus-Eledone moschata) were investigated. The results showed that lipid levels ranged from 0.75% to 1.60% in both muscle types of octopuses which were considered as lean. Lipid levels in mantle tissues of both octopus species were hig...

This study was conducted to assess the drinking water quality of north Mecha district, Amhara Region, Ethiopia. 26 samples were collected from points dweller community in dry seasons 2020 and subjected analysis physicochemical parameters, bacteriological level trace metals. The parameters metals carried out following standard procedures laboratory, qualities measured using membrane filtration m...

The EPA uses an exposure assessment model to estimate daily intake to chemicals of potential concern. At the Anaconda Superfund site in Montana, the EPA exposure assessment model was used to predict total and speciated urinary arsenic concentrations. Predicted concentrations were then compared to concentrations measured in children living near the site. When site-specific information on concent...