hepatocellular carcinoma (hcc) is very rare during pregnancy and has a worse prognosis in pregnant women compared to those who are not pregnant. we present a case of hcc in a 41- year-old pregnant patient who was referred to our academic hospital. the patient presented with chief complaints of abdominal pain, jaundice, edema and hypertension. laboratory results were notable for elevated liver e...

INTRODUCTION To examine pregnancy and delivery characteristics of women with and without vulvodynia. METHODS The authors analyzed 227 vulvodynia cases that were less than 45 years old at pain onset; controls were age matched 1:1 to cases and had no history of vulvar pain. Pregnancy and delivery events were assessed after age at first vulvar pain onset (the reference age) in cases and a matche...

Accounting for less than 5% of all vulvar malignancies, primary carcinoma of the Bartholin gland is rare. Cancers arising in the Bartholin duct are most commonly adenocarcinomas or squamous cell carcinomas; occasionally transitional cell, adenosquamous, and adenoid cystic carcinomas may develop. A case of locally advanced Bartholin gland carcinoma was seen recently at Mayo Clinic. Case Report

The present study reports the role of galectin-7 (Gal-7) expression in vulvar squamous cell carcinoma (VSCC) and its correlation with clinicopathological variables. Gal-7 expression was immunohistochemically detected in the paraffin-embedded sections of 20 normal vulvar biopsy samples and 50 VSCC specimens. Expression was also detected in 10 normal vulvar biopsy samples and 10 VSCC specimens by...

O condiloma acuminado gigante (tumor de Buschke-Loewenstein) apresenta comportamento clínico destrutivo, embora histologicamente benigno, início. Descreve-se caso localização vulvar e ano-retal com transformação maligna para carcinoma espinocelular invasivo. A paciente foi tratada radioterapia pré-operatória seguida excisão local ampla, evolução favorável. Os autores fazem revisão pormenorizada...

INTRODUCTION Vulvar cancer in older women is seldom associated with human papillomavirus infection. CASE PRESENTATION We present the case of an 80-year-old Greek Caucasian woman with an undetermined obstetric and gynecologic history. The patient underwent radical vulvectomy and bilateral inguinal lymphadenectomy for a vulvar carcinoma. A human papillomavirus infection was suggested on the bas...

•Sebaceous carcinoma (SC) is rare with only nine cases reported in the literature.•Extraocular SC likely has similar prognosis to ocular SC.•Reporting of vulvar SC should include detailed pathologic information so that risk factor associations can be made.

EPIDEMIOLOGY Vulvar cancer can be classified into two groups according to predisposing factors: the first type correlates with a HPV infection and occurs mostly in younger patients. The second group is not HPV associated and occurs often in elderly women without neoplastic epithelial disorders. HISTOLOGY Squamous cell carcinoma (SCC) is the most common malignant tumor of the vulva (95%). CL...

This is a new case of Merkel cell carcinoma of the vulva. It is a rare neuroendocrine carcinoma with an aggressive behavior. Because of its rarity in this location, it is not clear whether it behaves differently from the usual neuroendocrine carcinomas of the skin. A case of a 63-year-old patient with vulvar Merkel carcinoma is presented. The clinical presentation, microscopic and immunohistoch...