1. Protogerou AD, Blacher J, Mavrikakis M, Lekakis J, Safar ME: Increased pulse pressure amplification in treated hypertensive subjects with metabolic syndrome. Am J Hypertens 2007;20:127–133. 2. Safar ME, Smulyan H: Hypertension in women. Am J Hypertens 2007;17:82–87. 3. Safar ME: Systolic blood pressure, pulse pressure and arterial stiffness as cardiovascular risk factors. Curr Opin Nephrol H...

When a stroke volume of arterial blood arrives to the brain, the total blood volume in the bony cranium must remain constant as the proportions of arterial and venous blood vary, and by the end of the cardiac cycle an equivalent volume of venous blood must have been ejected. I hypothesize the brain to support this process by an extraluminally mediated exchange of information between its arteria...

To study the peripheral blood flow in patients with panic attacks during "Stress" conditions, nine patients with history of panic attacks were subjected to mental stress of arithmetic calculation and room-air voluntary hyperventilation. Finger Pulse Volume (FPV) was significantly altered during the period following mental activity in untreated patients when compared to controls and patients und...

In six anaesthetised and ventilated dogs the CSF pulse pressure was compared with the volume-pressure response (VPR) during continuous inflation of an extradural balloon. Both pulse pressure and VPR increased linearly with the ventricular fluid pressure (VFP) up to a mean VFP of 60 mmHg. At this pressure a breakpoint occurred above which the CSF pulse pressure showed a steeper linear increase, ...

BACKGROUND Markers of temporal changes in central blood volume are required to non-invasively detect hemorrhage and the onset of hemorrhagic shock. Recent work suggests that pulse pressure may be such a marker. A new approach to tracking blood pressure, and pulse pressure specifically is presented that is based on a new form of pulse pressure wave analysis called Pulse Decomposition Analysis (P...

BACKGROUND Although the existence of myocardial mechanoelectrical feedback is well established, the mechanism of arrhythmia induction by ventricular dilatation or stretch remains insufficiently defined. In particular, controversy exists when comparing the arrhythmogenic potential of chronic versus acute myocardial stretch. Also, assessment of cellular electrophysiological effects of myocardial ...

Which means that SVV (%) ≈ pulse pressure variation (PPV; %) for FloTracTM. With the present mathematical equation, it can be demonstrated that the SVV calculated by FloTracTM (SVVFT) is not infl uenced by Khi, which means that SVVFT calculation does not include eff ective arterial elastance (Ea). Th e originality of Garcia and colleagues’ fi nding is that they realized that when measuring PPV ...

A high power polarization maintaining femtosecond Tm-doped fiber laser system is demonstrated. A chirped fiber Bragg grating with normal dispersion was used to compensate the anomalous dispersion from the regular fiber in the 2 µm seed oscillator to generate mode locked pulses with a pulse repetition rate of 30.84 MHz. After chirped pulse amplification, an amplified power of 78 W was obtained. ...