Devices made of few molecules constitute the miniaturization limit that both inorganic and organic-based electronics aspire to reach. However, integration of millions of molecular junctions with less than 100 molecules each has been a long technological challenge requiring well controlled nanometric electrodes. Here we report molecular junctions fabricated on a large array of sub-10 nm single c...

Action potentials and voltage-gated currents were studied in acutely dissociated neurosecretory cells from the rat supraoptic nucleus during the first three postnatal weeks (PW1-PW3), a period corresponding to the final establishment of neuroendocrine relationships. Action potential duration (at half maximum) decreased from 2.7 to 1.8 ms; this was attributable to a decrease in decay time. Appli...

Molecular junctions formed using the scanning-tunneling-microscope-based break-junction technique (STM-BJ) have provided unique insight into charge transport at the nanoscale. In most prior work, the same metal, typically Au, Pt, or Ag, is used for both tip and substrate. For such noble metal electrodes, the density of electronic states is approximately constant within a narrow energy window re...

In neocortical pyramidal neurons, the medium (mAHP) and slow AHP (sAHP) have different relationships with intracellular [Ca2+]. To further explore these differences, we varied bath temperature and compared passive and active membrane properties and Ca2+ transients in response to a single action potential (AP) or trains of APs. We tested whether Ca(2+)-dependent events are more temperature sensi...

the supply voltage to reduce dynamic power consumption in CMOS devices, inadvertently will lead to an exponential increase in leakage power dissipation. In this work we explore an architectural idea to reduce leakage power in data caches. Previous work has shown that cache frames are " dead " for a significant fraction of time [14]. We are exploiting this observation to turn off cache lines tha...

Dynamic response of a dual-frequency liquid crystal (DFLC) based near infrared phase modulator is investigated through numerical simulations and experiments. The relationships between the optical response times and various voltage driving conditions are studied. An optical phase retarder operating at 1.55 lm wavelength is demonstrated by using our homemade high figure-of-merit DFLC mixture. To ...

Regulation of spike frequency adaptation has been postulated to be a neuronal mechanism of action of the barbiturates (Zbicz and Wilson, 1981). A barbiturate sensitive slow outward current is present in Aplysia giant neurons, and this current is very effective at regulating adaptation. In the current study a quantitative method of determining the effect of barbiturates was developed using a sin...

Expressions for the moments of the membrane potential in Stein's model with synaptic (excitatory and inhibitory) reversal potentials are presented. The mean and variance of the voltage trajectories are used to approximate the mean and standard deviation of the interspike intervals under certain conditions (Stein, 1967) that yield a small coefficient of variation. The limiting case of excitatory...

We classify and analyze bit errors in the current measurement mode of the Kirchhoff-law– Johnson-noise (KLJN) key distribution. The error probability decays exponentially with increasing bit exchange period and fixed bandwidth, which is similar to the error probability decay in the voltage measurement mode. We also analyze the combination of voltage and current modes for error removal. In this ...