Ketamine is a popular choice for young drug abusers. Ketamine abuse causes lower urinary tract symptoms, with the underlying pathophysiology poorly understood. Disruption of urothelial barrier function has been hypothesized to be a major mechanism for ketamine cystitis, yet the direct evidence of impaired urothelial barrier function is still lacking. To address this question, 8-wk-old female C5...

conclusions the use of midazolam 0.5 mg/kg reduced children's stress and increased their cooperation during the procedure. objectives the purpose of our study was to compare using oral midazolam in contrast to prescribing no sedative medication for voiding dysfunction in children undergoing vcug. patients and methods in a clinical trial, we studied 84 children referred for vcug. children were a...

PURPOSE We aimed to assess the value of video-urodynamic study (VUD) in the identification of lower urinary tract voiding dysfunction in female recurrent urinary tract infections (UTIs). PATIENTS AND METHODS A total of 54 women with recurrent UTIs who underwent VUDs between 2013 and 2015 were analyzed. They were carefully evaluated by complete history, voiding diary, physical investigation, u...

Multiple sclerosis (MS) is a devastating neurologic disease that attacks young adults and affects all aspects of their lives. Genitourinary dysfunction in MS has a significant impact on quality of life with more than 80% of those with MS reporting genitourinary symptoms. Voiding dysfunction is a prominent problem affecting the majority of MS sufferers. Less commonly recognized, but of no less i...