Accumulating evidence in humans demonstrates that visuo-spatial deficits are the most consistently reported cognitive abnormalities in Parkinson's disease (PD). Ezrin, radixin, and moesin are collectively known as ERM proteins. Although ERM proteins have important implications in cell-shape determination and relevant signaling pathway, they have not been studied in the hippocampus in associatio...

Recent studies in humans and monkeys have reported that acoustic stimulation influences visual responses in the primary visual cortex (V1). Such influences can be generated in V1, either by direct auditory projections or by feedback projections from extrastriate cortices. To test these hypotheses, cortical activities were recorded using optical imaging at a high spatiotemporal resolution from m...

This paper presents a strategy to build an experimental visuo-motor model for a manipulator coupled to a binocular vision system, which discards any previous algebraic model and any calibration of either the manipulator or the vision system. The space spanned by a set of selected image features is divided in regions, and the estimated visuo-motor model is represented by a matrix of constant ele...

The correlation between arithmetic dysfunction and brain laterality was studied in 25 children with developmental dyscalculia (DD). The children were tested on a standardized arithmetic battery and underwent a neurological and neuro-psychological evaluation. A diagnosis of left hemisphere dysfunction (n = 13) was based on right side soft neurological signs, performance IQ (PIQ) > verbal IQ (VIQ...

It is still a matter of debate whether constructive apraxia (CA) should be considered a form of apraxia or, rather, the motor expression of a more pervasive impairment in visuo-spatial processing. Constructive disorders were linked to visuo-spatial disorders and to deficits in appreciating spatial relations among component sub-parts or problems in reproducing three-dimensionality. We screened a...

Peripersonal space processing inmonkeys’ brain relies on visuo-tactile neurons activated by objects near, not touching, the animal’s skin.Multisensory interplay inperipersonal space is nowwell documented also inhumans, inbraindamagedpatientspresenting cross-modal extinctionaswell as inhealthy subjects and typically takes the form of stronger visuo-tactile interactions in peripersonal than far s...

The representation of one's own body sets the border of the self, but also shapes the space where we interact with external objects. Under particular conditions, such as in the rubber hand illusion external objects can be incorporated in one's own body representation, following congruent visuo-tactile stroking of one's own and a fake hand. This procedure induces an illusory sense of ownership f...

Architects deal with visual/spatial features and organization of larger scale real world elements than other domains. The use of mental imagery in the architectural design process is the key issue to transform and mimic the spatial aspects of the environment. Depending on the focus of the design process, the use of imagery could relate directly to visuo-spatial aspects, or could be about manipu...