Objective(s): Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro. Materials and Methods:The effect of apatinib in colon cancer cells were detected by assessing cell ...

Background: Arteriovenous malformations are one of the most common vascular disorders of the colon. Vascular disorders present as painless, high-volume rectal bleeding. Case Presentation: This study elucidates two rare cases of vascular disorders that are diagnosed as angiodysplasia of the left colon and cavernous hemangioma of the colon and rectum.  The chief complaint in two patients ...

the aim of this paper is to introduce new methods of colorectal and anus surgeries. it is not a comprehensive paper and just is a summary of issues related to colon surgeries due to intestinal inflammatory diseases (ulcerative colitis and crohn's disease), and anus cancer. ulcerative colitis usually initiates from rectum and then develops upward to colon. there are three methods of surgery...

Background: The equine colic, which is caused by the presence of enteroliths that are most often found in the small or large colon, is typical for certain geographical regions (dry and hot climate). A diet rich in alfalfa is one of the highest risk factors. The earliest symptoms include weight loss and repeated episodes of colic pain. Aims: To present the resul...

BACKGROUND The aim of this study was to assess the effect of diet supplementation with L-ascorbic acid (500 mg/L), tocopherol (3 mg/kg b.w.), and/or a water soluble analog of tocopherol (Trolox) (48 mg/L) on ion transport in the colon of rats subjected to a chronic exposure (9 months) to 0.1% lead acetate in drinking water. MATERIAL/METHODS The electrophysiological parameters of the colon wal...

Background. Colorectal cancer (CRC) is a growing public health concern with increasing rates in countries with previously known low incidence. This study determined pattern and distribution of CRC in Tanzania and identified hot spots in case distribution. Methods. A retrospective chart audit reviewed hospital registers and patient files from two national institutions. Descriptive statistics, Ch...

Over the last decade, WCE has established itself as a valuable test for imaging the small intestine. It is a safe and relatively easy procedure to perform that can provide valuable information in the diagnosis of small-bowel conditions. Its applications still remain limited within the esophagus and colon. Future developments may include improving visualization within the esophagus and developin...

been frequently reported in literature, but almost all the reported AVMs were angiodysplasias. Unlike AVM that has a congenital origin, angiodysplasia is a degenerative disease usually present in elderly patients. Intestinal AVMs are very rare, and only a few cases have been reported (1, 2). Here, we report a case of an intestinal AVM, and discuss the confusion between the 2 terminologies-AVM a...

background: colorectal cancer is a common and lethal disease with various distribution of incidence in different part of the world and it is known as the third most common cause of cancer death in the world. since several studies in the world represented different survival rates for colorectal cancer in this study we aimed to determine the survival of a group of iranian patients and some relate...