Viral inclusion bodies (VIBs) are specific intracellular compartments for reoviruses replication and assembly. Aquareovirus nonstructural protein NS80 has been identified to be the major constituent for forming globular VIBs in our previous study. In this study, we investigated the role of NS80 in viral structural proteins expression and viral replication. Immunofluorescence assays showed that ...

Viroporins are involved in viral pathogenesis, play an important role the morphogenesis of virions and ensure their release from infected cell. These proteins potentially promising as possible targets for regulation virus reproduction. The literature data on current understanding coronavirus viroporins functioning summarized review. Special attention is focused specific structural features that...

Viral assembly was thought to occur only in the cell body, with subsequent transport of fully assembled virions to axon terminals for release. Indeed, a pseudorabies virus mutant for Us9 appeared to be defective only in the second step, as it still makes infectious viral particles in the cell body but is defective for viral shedding from axons. But Tomishima and Enquist find that in the Us9 mut...

Viral assembly was thought to occur only in the cell body, with subsequent transport of fully assembled virions to axon terminals for release. Indeed, a pseudorabies virus mutant for Us9 appeared to be defective only in the second step, as it still makes infectious viral particles in the cell body but is defective for viral shedding from axons. But Tomishima and Enquist find that in the Us9 mut...

Viral assembly was thought to occur only in the cell body, with subsequent transport of fully assembled virions to axon terminals for release. Indeed, a pseudorabies virus mutant for Us9 appeared to be defective only in the second step, as it still makes infectious viral particles in the cell body but is defective for viral shedding from axons. But Tomishima and Enquist find that in the Us9 mut...