Hepatitis C virus (HCV) is a hepatotropic virus and a major cause of chronic hepatitis and liver disease worldwide. Initial interactions between HCV virions and hepatocytes are required for productive viral infection and initiation of the viral life cycle. Furthermore, HCV entry contributes to the tissue tropism and species specificity of this virus. The elucidation of these interactions is cri...

The prevalence of Hepatitis C virus (HCV) is approximately 3% around the world. This virus causes chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The effectiveness of interferon-α and ribavirin therapy is about 50% and is associated with significant toxicity and cost. Hence, generating new vaccines or drugs is an obligation. However, there is no vaccine available for clinical u...

REFERENCES Genotype 1 Hepatitis C Virus (HCV) chronic infection is a public health problem in Colombia. The natural course of the disease generates a significant humanistic and economic burden, especially because of long term medical complication. Unlike other viral diseases which could be prevented through vaccines, the only alternative to avoid further HCV complications is the early detection...

Introduction: Hepatitis B and C are major health problems in many countries, especially developing areas. The frequency of hepatitis B is less than 0.8%, and chronic hepatitis C is less than 0.5% in the general population of Yazd in the center of Iran. Large vehicle drivers have some risk factors for acquiring hepatitis B and C infection. This is important because viral hepatitis complications,...

background: triple-course vaccination against hepatitis b might sometimes fail to increase antibody titers or maintain it at sufficient levels. the aim of this study was to evaluate the rate of seroprotection in dental students after receiving recombinant hepatitis b vaccine.     methods: anti-hbs levels of 124 dental students who had received triple-course hepatitis b vaccines (scheduled at mo...

E suggests a linkage between different environmental agents and the development of celiac disease—an immune-mediated disorder—in those with a specific genetic predisposition (HLADQ2, HLA-DQ8) who exposed to gluten—a major storage protein in wheat and other grains. Infections, particularly viral agents, have been hypothesized to induce or exacerbate immune-mediated disorders, possibly through a ...

Viral hepatitis is a disease burden in Africa and globally. It can be caused by RNA or DNA virus, which hepatotropic pose financial on the individual, their family, society. Hepatitis B virus (HBV) that present blood body fluids, including saliva, semen, vaginal secretion. par-enterally transmitted with horizontal vertical transmission. The risk of infection transmission could result occupation...

Hepatitis E virus (HEV) is a common etiology of acute viral hepatitis worldwide. Recombinant HEV vaccines have been developed, but only one is commercially available and licensed in China since 2011. Epidemiological studies have identified genotype 3 as the major cause of chronic infection in immunocompromised individuals. Ribavirin has been shown to be effective as a monotherapy to induce HEV ...

Cancer immunoprevention is an emerging field that holds much promise. Within the past 20 years, prophylactic vaccines have been implemented on the population level for the immunoprevention of carcinomas induced by viruses, specifically hepatitis B virus (HBV) and human papillomavirus (HPV) infection. Armed with the success of prophylactic vaccines that prevent viral-induced tumors, the field mu...