background: the mean platelet volume (mpv) is the most commonly used measure of platelet size and is a potential marker of platelet reactivity. in this study, we aimed to explore the relationship between hepatic  histopathology in viral hepatitis and mpv levels,which are associated with platelet count and activity. materials and methods: we performed a retrospective case-control study of baseli...

conclusions this study showed that the presence of mutation at codons rtl80v, rtl180m and rtm204v in a, b and c domains is associated with higher viral load and resistance to lamivudine (3tc) respectively. results about 6% (3 of 50) of samples were hbeag positive and 94% (47 of 50) of patients were hbeag negative by elisa method. the patients' alt level was between 16 and 95 iu/l with the mean ...

In a 4-month period, 216 cases of acute viral hepatitis were diagnosed in adults at the Infectious Diseases Hospital, Athens, Greece. Twenty-six percent of these were hepatitis B surface antigen negative. A full set of clinical specimens was obtained from 19 of these patients, who were studied in depth for the etiology of their hepatitis. A total of 7 of the 19 patients had serological evidence...

background: hepatitis activity index (hai) and fibrosing stage are two important findings during the evaluation of liver samples in patients with chronic hepatitis b. the aim of this study was to determine the hai and fibrosing stage in patients with anti-hbe positive chronic hepatitis b. methods: liver biopsy slides of 72 patients were evaluated at the department of pathology in two teaching h...

Treatment of chronic hepatitis B remains a clinical challenge. Long-term viral suppression is a major goal of antiviral therapy to improve the clinical outcome of the patients. Antiviral treatment of chronic hepatitis B relies currently on immune modulators such as interferon alpha and its pegylated form, and viral polymerase inhibitors. Because of the slow kinetics of viral clearance and the s...

800x600 background : hepatitis b and c infections have remained major global health burdens during the most recent century. the viral agents responsible for these diseases share common modes of transmission with human immunodeficiency virus (hiv) such as needle-sharing in iv drug abusers. coinfection of hepatitis b or c with hiv increases the rate of progression of chronic liver disease. given ...

conclusions a significant direct correlation was observed between the viral dna copies present in patients’ cerumen and serum. however, the correlation between saliva viral load with serum and cerumen viral load was very low and inverse. these findings suggest that the presence of the hepatitis b virus (hbv) in non-invasive specimens (such as cerumen and saliva) should also be evaluated when mo...