نتایج جستجو برای: vinca herbacea extract

تعداد نتایج: 177882  

2012
M. Bhanu Prakash Subhankar Paul

In the present study, silver nanoparticles were rapidly green synthesized from AgNO3 solution using leaf extract of Vinca Roseus at room temperature. The green synthesized Silver Nanoparticles were characterized by UV–Visible absorption spectroscopy and further by analytical techniques such as, DLS, X-ray diffraction (XRD) and SEM. X-ray diffraction and Scanning Electron Microscope analysis stu...

Journal: :journal of agricultural science and technology 2012
j. h. lee h. j. kim j. w. rhim

vacuum drying of salicornia herbacea l. was performed at different drying temperatures (50, 60, 70, and 80c) to evaluate the drying characteristics and the effect of drying temperatures on the quality of salicornia. as the drying temperature increased, the drying time decreased significantly (p< 0.05). the drying rate decreased with decrease in moisture content and increase in drying time. on ...

Journal: :FEBS Letters 2021

Tubulin vinca-domain ligands can inhibit microtubule polymerization, causing cell death in mitosis, and their potential against multiple cancer types has been demonstrated. However, due to drug resistance toxicities, development of novel is still needed. In this study, we determined the high-resolution crystal structures vinorelbine, YXD, Phomopsin A complex with tubulin at 2.5 Å. Additionally,...

Journal: :Medical research archives 2022

Vinca alkaloids used in anticancer therapy are the well-known vinblastine and vincristine as classical antitumor agents. These dimeric molecules consist of two monomers, vindoline catharanthine, which have no particular activity on their own. The goal our research work was to obtain derivatives one these, vindoline, resulted with important antiproliferative effect. This type were hybrids; conju...

Journal: :Indian journal of physiology and pharmacology 2005
M Kaleem Sheema H Sarmad B Bano

In the present study aqueous extract of Piper nigrum seeds and Vinca rosea flowers were administered orally to alloxan induced diabetic rats once a day for 4 weeks. These treatments lead to significant lowering of blood sugar level and reduction in serum lipids. The levels of antioxidant enzymes, catalase and glutathione peroxidase decreased in alloxan induced diabetic rats however these levels...

Journal: :Molecular cancer therapeutics 2003
Tatiana Okouneva Bridget T Hill Leslie Wilson Mary Ann Jordan

Vinflunine is a novel fluorinated Vinca alkaloid currently in Phase II clinical trials, which in preclinical studies exhibited superior antitumor activity to that of two clinically useful Vinca alkaloids, vinorelbine and vinblastine. All three of the drugs block mitosis at the metaphase/anaphase transition, leading to apoptosis. The mechanism of the mitotic block is not known. On the basis of r...

Journal: :Journal of Environmental Horticulture 2005

Journal: :The Journal of biological chemistry 2003
Nicole M Verrills Bradley J Walsh Gary S Cobon Peter G Hains Maria Kavallaris

Vinca alkaloids are used widely in the treatment of both childhood and adult cancers. Their cellular target is the beta-tubulin subunit of alpha/beta-tubulin heterodimers, and they act to inhibit cell division by disrupting microtubule dynamics. Despite the effectiveness of these agents, drug resistance is a major clinical problem. To identify the underlying mechanisms behind vinca alkaloid res...

Journal: :iranian journal of pharmaceutical research 0
behnaz farahanikia department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran. tahmineh akbarzadeh department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran. akbar jahangirzadeh department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran. narguess yassa department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran. mohammad reza shams ardekani department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran. tahmineh mirnezami department of pharmacognosy and medicinal plants research center, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

lesser periwinkle (vinca minor l.), a member of apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. this plant is native to northern spain, western france, central and southern europe, and caucasus. it has been rece...

Journal: :Jordan Journal of Pharmaceutical Sciences 2022

The study aimed to investigate extracts of un-ripe pods Vinca rosea cv. Pink for antidiabetic activity and polyphenol-based characterization using HPLC. Moreover, the molecular interaction identified markers with targets was explored molecular-docking software. Different were prepared investigated models such as glucose uptake by yeast cells, alpha amylase inhibition haemoglobin-glycosylation a...

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