In recent years, there have been important changes in antimicrobial therapy. New antimicrobials are available and a greater database of species-specific pharmacokinetic information is available, allowing for more accurate dosing with drugs. Antimicrobial drugs are the most widely prescribed and administered drugs in veterinary medicine. Unfortunately, they are not always used appropriately. In ...

has been a hotly debated issue in the US. The initial issue was the effect of drugs, chiefly antibiotics, on cheese manufacturing processes. Reports in the press highlighting contamination of milk and other dairy products with antibiotics and other animal drugs quickly raised the issue of food safety and resulted in the intervention of governmental agencies regulating the use of animal medicati...

INTRODUCTION Antibiotic therapy has made many advances that has given veterinary medicine a large number of effective drugs and provided pharmacokinetic and pharmacodynamic information to guide dosing. Improved techniques for bacterial identification and susceptibility testing have helped to provide information for the most appropriate drug selection. This presentation will review the current c...

Ultra-performance liquid chromatography combined with time-of-flight mass spectrometry (UPLC-ToF-MS) has been used for screening and quantification of more than 100 veterinary drugs in milk. The veterinary drugs represent different classes including benzimidazoles, macrolides, penicillins, quinolones, sulphonamides, pyrimidines, tetracylines, nitroimidazoles, tranquillizers, ionophores, ampheni...

OBJECTIVES The objectives were (i) to identify occupational populations outside hospitals working with antineoplastic drugs, (ii) to determine the size of the populations 'at risk', (iii) to identify major determinants and routes of exposure outside hospitals and (iv) to estimate exposure levels and frequencies relative to levels found in hospitals. METHODS The survey consisted of two phases;...

Background: Closantel is a veterinary drug used as anthelmintic for ruminants while it is contraindicated for humans. This report describes a rare case of blindness, increased liver enzymes and coagulopathy following closantel poisoning. Case report: A 5-year-old girl was presented with acute blindness following closantel poisoning. She was given mistakenly a dose of 500 mg/day (25mg/kg/day) fo...

Drugs, hormones and pesticides are chemical compounds used for alleviation of various diseases in animals. There are many classes of drugs which have been used and in the case of natural steroid hormones these have been used to increase mass gain by stimulating protein anabolism. Pesticides have been used for many years in the control of ectoparasites which transmit important human and livestoc...