INTRODUCTION Seminal vesicle cysts are rarely diagnosed, but symptomatic congenital seminal vesicle cysts are reported in the literature describing Zinner syndrome. CASE DESCRIPTION We present the case of a 26-year-old patient admitted to the urology department because of abdominal pain. A left seminal vesicle cyst and left kidney agenesis were found on examination, and the patient qualified ...

Dermatitis Herpetiformis is a chronic autoimmune blistering skin condition that often associated with gluten-sensitive enteropathy. The primary lesion of DH an erythematous papule, plaque, or, most commonly, vesicle can be pruritic.

A method combined the self-consistent field theory (SCFT) for the rigid rod with the Helfrich curvature elasticity theory for the vesicle has been developed for studying the shape of vesicles anchored by rigid rod. Both the deformation of the vesicle and the density distribution of rod segments can be obtained. Because of the vesicle's impenetrability for the rod segments and the decrease of th...

As a step toward the elucidation of mechanisms in vesicle budding, a cell-free assay that measures cytosol-induced vesicle generation from liposomes was established. This assay then was used to explore the role of phosphoinositides in vesicle formation. Liposomes incubated with brain cytosol in the presence of ATP and GTP massively generated small vesicles, as assessed both quantitatively and q...

Exocytosis is the process of fusion of a membrane-bound vesicle with the cell membrane and subsequent release of the vesicle content to the outside. It is now widely accepted that SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) proteins are key components in the molecular machinery of exocytosis. SNARE proteins on the vesicle membrane selectively form complexes w...

We report the collision behavior of single unilamellar vesicles, composed of a bilayer lipid membrane (BLM), on a platinum (Pt) ultramicroelectrode (UME) by two electrochemical detection methods. In the first method, the blocking of a solution redox reaction, induced by the single vesicle adsorption on the Pt UME, can be observed in the amperometric i-t response as current steps during the elec...

Vesicle trafficking is a highly regulated process that transports proteins and other cargoes through eukaryotic cells while maintaining cellular organization and compartmental identity. In order for cargo to reach the correct destination, each step of trafficking must impart specificity. During vesicle formation, this is achieved by coat proteins, which selectively incorporate cargo into the na...

Although several proteins have been implicated in secretory vesicle tethering, the identity and mechanical properties of the components forming the physical vesicle-plasma membrane link remain unknown. Here we present the first experimental measurements of nanomechanical properties of secretory vesicle-plasma membrane tethers using combined AFM force clamp and TIRF microscopy on membrane sheets...