Lichen sclerosus is a chronic inflammatory disease that can progress to malignancy. The literature indicates an association with anogenital squamous cell carcinoma and verrucous carcinoma. Two pathogenic pathways, differentiated vulvar and penile intraepithelial neoplasias, which have recently been described in relation to squamous cell carcinoma, are both highly associated with genital lichen ...

BACKGROUND Was to describe 14 cases of a proliferative verrucous leukoplakia as a clinical evolution of oral lichen planus. MATERIAL AND METHODS The clinical and histopathological characteristics of 14 cases of OLP that progress towards a plaque-like and verrucous form were indicated, with monitoring over a period of six to 24.3 years. RESULTS The female/male ratio was 11/3, (78.6 and 21.4%...

BACKGROUND Verrucous carcinoma is a rare variant of well-differentiated squamous cell carcinoma of the uterine cervix. Infection with high-risk human papillomavirus (HPV) is the main cause of intraepithelial and invasive neoplasias of the female genital tract, but the aetiology of verrucous carcinoma is still unknown. The aim of this study was to evaluate the presence of HPV in verrucous carcin...

Verrucous carcinoma is a rare, well-differentiated variant of squamous cell carcinoma with a minimal incidence of metastasis. Conservative treatment and local excision have been utilized although with high recurrence rates. We present a unique case of a 44-year-old male with bilateral foot involvement with recurrences after local excision, leading to management with bilateral forefoot amputations.

OBJECTIVE To determine the prevalence of human papillomavirus (HPV) DNA in penile cancers in Rio de Janeiro, Brazil. MATERIALS AND METHODS We studied, prospectively, 80 consecutive cases of patients with penile cancers who underwent surgical treatment at three different Hospitals in Rio de Janeiro between March 1995 and June 2000. Of these patients, 72 were diagnosed with invasive squamous ce...

Dear Editor, Verrucous carcinoma (VC) is a rare variant of squamous cell carcinoma with low grade, well-differentiated, and very slow-growing malignancy. Due to its local invasiveness and recurrence, the treatment of choice is surgical excision with clear margins. We report a case of a female patient with eyelid VC. A 78-year-old woman presented with a growing mass on the right medial canthal a...

Syringocystadenoma papilliferum (SP) commonly arises in conjunction with nevus sebaceous. Other less common lesions reported with SP include apocrine adenoma, condyloma acuminatum, hidradenoma papilliferum associated with hidrocystoma, poroma folliculare, and a single case ofverrucous carcinoma. We report the second case of verrucous carcinoma in conjunction with SP.