OBJECTIVE To characterize changes in cognition that occur during the hormonal transitions of menopause. METHOD We conducted a longitudinal population-based study in Kinmen, Taiwan, recruiting all women age 40-54 years who were premenopausal and without a history of hormone replacement therapy (HRT) or hysterectomy. The cognitive measures used to assess function included the Auditory-Verbal Le...

OBJECTIVE Schizophrenia and bipolar disorder are characterized by the presence of neurocognitive impairments on the psychosis continuum. The present study aimed to explore the shared and distinct endophenotypes between these disorders. METHODS The study included 34 probands with remitted schizophrenia and 34 probands with euthymic bipolar disorder who had a history of psychotic symptoms that ...

Evidence from neuroimaging and cerebellar lesion studies indicate that the cerebellum plays a role in language articulation and verbal fluency. Previous studies have established that distinct areas of the cerebellum are differentially active during each of these tasks, with articulation engaging the anterior cerebellum and verbal fluency activating areas of the right posterolateral cerebellum. ...

The association between verbal fluency deficit in Alzheimer's disease (AD) and deterioration of specific white matter (WM) tracts is currently not well understood. Using diffusion tensor imaging, we investigated a possible association between the left uncinate fasciculus, which has been implicated in word retrieval, and verbal fluency deficit in AD. A comparison of five properties of WM (fracti...

Over the last few years, numerous studies have attempted to explain fluency impairments in people with schizophrenia, leading to heterogeneous results. This could notably be due to the fact that fluency is often used in its verbal form where semantic dimensions are implied. In order to gain an in-depth understanding of fluency deficits, a non-verbal fluency task - the Five-Point Test (5PT) - wa...

BACKGROUND Verbal fluency relies on the coordinated activity between left frontal and temporal areas. Patients with Parkinson's disease (PD) present phonemic and semantic fluency deficits. Recent studies suggest that transcranial direct current stimulation (tDCS) enhances adaptative patterns of brain activity between functionally connected areas. OBJECTIVE The aim of this study was to assess ...

Background: Verbal fluency relies on the coordinated activity between left frontal and temporal areas.Patients with Parkinson’s disease (PD) present phonemic and semantic fluency deficits. Recent studiessuggest that transcranial direct current stimulation (tDCS) enhances adaptative patterns of brain activitybetween functionally connected areas.Objective: The aimof this studywas ...

We used multidimensional statistical procedures to study semantic and lexical processes underlying word retrieval in verbal-fluency performance. Forty healthy participants were given a two-choice letter task (i.e., generate items beginning with the letter 'A' or 'F', in any order) and a two-choice category task (i.e., generate animal or fruit names, in any order). Using correspondence analysis ...

In a community-dwelling sample (N = 4,790; age range 14-94), we examined whether personality traits prospectively predicted performance on a verbal fluency task. Open, extraverted, and emotionally stable participants had better verbal fluency. At the facet level, dispositionally happy and self-disciplined participants retrieved more words; those prone to anxiety and depression and those who wer...

OBJECTIVE The aim of this study was to evaluate the neurobehavioral safety of constant-current subthalamic deep brain stimulation and to compare the neuropsychological effects of stimulation versus electrode placement alone. METHODS A total of 136 patients with Parkinson's disease underwent bilateral subthalamic device implantation in this randomized trial. Patients received stimulation eithe...