OBJECTIVE To analyze the relation between vitamin D insufficiency and wound healing in patients with venous ulcers; to correlate vitamin D insufficiency with characteristics of the ulcer (size and pain) and to evaluate if reposition of vitamin D in these subjects expedites ulcer healing. METHODS We selected 26 patients with leg ulcers, and 26 control patients without ulcers, matched for gende...

Venous leg ulcers are an important medical issue due to their high incidence in the elderly and the lack of a standard curative approach. Apart from surgical therapy, different medical treatments to effect ulcer wound repair and regeneration are currently being investigated. Sucralfate is a cytoprotective agent employed to prevent or treat several gastrointestinal diseases such as gastroesophag...

OBJECTIVE To determine the effect of oxpentifylline on the healing of venous ulcers of the leg. DESIGN Double blind, randomised, prospective, placebo controlled, parallel group study. SETTING Four outpatient clinics treating leg ulcers in England and the Republic of Ireland. PATIENTS 80 Consecutive patients with clinical evidence of venous ulceration of the leg in whom appreciable arteria...

OBJECTIVE To identify and describe the qualitative variations in how physical activity is perceived and understood by individuals with current or previous venous leg ulcer. DESIGN A qualitative study using semi-structured interviews. METHOD Twenty-two individuals aged 60-85 years were interviewed. The interviews were recorded, transcribed verbatim and analysed by three researchers using a p...

OBJECTIVES The aim was to assess vein recanalisation and ulcer recurrence in patients with chronic venous ulceration following ultrasound-guided foam sclerotherapy. METHOD Open (CEAP 6) or recently healed (CEAP 5) chronic venous leg ulcers were treated with foam sclerotherapy between July 2010 and August 2012. Venous duplex scans were performed two weeks and one and two years post treatment, ...

OBJECTIVE We undertook this cross-sectional study to investigate the distribution of venous reflux and effect of axial reflux in superficial and deep veins and to determine the clinical value of quantifying peak reverse flow velocity and reflux time in limbs with chronic venous disease. PATIENTS AND METHODS Four hundred one legs (127 with skin changes, 274 without skin changes) in 272 patient...

introduction: a traumatic arteriovenous fistula (avf) after repetitive blunt trauma has not been described previously. in a 34-year-old male, the first reported case of such an injury after repetitive blunt trauma is described. case presentation: a 34-year-old gentleman presented with a non-healing ulcer near his medial malleolus. a bone scan was performed and then treated for presumed osteomye...

AIM Leg compression bandaging is the mainstay of venous ulcer treatment, yet little is known about the impact of therapeutic compression levels on arterial haemodynamics. In this study, the effect of foot-to-knee, four-layer compression bandaging on below-knee arterial pulsatile blood flow was assessed by nuclear magnetic resonance flowmetry. METHODS In 14 healthy supine subjects, bilateral p...

BACKGROUND Venous leg ulceration is a frequent and severe complication of lower limb venous insufficiency. Compression therapy is associated with a protracted course of healing and multiple recurrences. Minimally invasive surgery (subfascial endoscopic perforating surgery) is only possible in a subset of patients with leg ulcers. Low-cost and noninvasive therapeutic procedures are needed as alt...

Introduction: Venous insufficiency (IV) is a condition in which the venous return presents itself as result of inadequate valves generating stasis. Objective: report on healing process ulcers using an inelastic compressive therapy Bota de Unna associated with sclerotherapy. Materials and methods: It case report, applied nature, explanatory descriptive objectives qualitative approach. Held non-p...