In this study, a group of 313 workers occupationally exposed to vinyl chloride monomer (VCM) and 141 normal unexposed referents were examined for chromosomal damage using the cytokinesis-blocked micronucleus (CBMN) assay in peripheral lymphocytes. We explored the relationship between genetic polymorphisms of XRCC1 (Arg194Trp, Arg280His and Arg399Gln), MGMT(Leu84Phe) and hOGG1 (Ser326Cys) and su...

This study was aimed at investigating the use of intra-testicular calcium chloride (CaCl2) and 4-vinylcyclohexene 1,2-monoepoxide (VCM) injections as a side effect-free alternative method for the control of reproduction in guinea pigs. Fifty male guinea pigs were randomly assigned to five groups. In all groups, the chemical agents were injected into both testes in 1% lidocaine hydrochloride. Wh...

a box-behnken design with three replicates was used for preparation and evaluation of eudragit vancomycin (vcm) nanoparticles prepared by double emulsion. the purpose of this work was to optimize vcm nanoparticles to improve the physicochemical properties. nanoparticles were formed by using w1/o/w2 double-emulsion solvent evaporation method using eudragit rs as a retardant material. full factor...

The Association of Plastic Manufacturers in Europe maintains a register of all cases of angiosarcoma of the liver (ASL) resulting from exposure to vinyl chloride monomer (VCM). This register has recorded all known VCM related cases of the disease worldwide that have been histologically confirmed. Although likely to be incomplete, it is the most comprehensive tabulation of such cases available a...

Vinyl chloride (VCM) is not carcinogenic by itself, it is bioactivated to the highly reactive alkylating oxirane chloroethylene oxide. Further metabolism, apparently, leads via an interaction of the primary alkylating metabolites with glutathion to S-(2-carboxy-methyl)-cysteine and thiodiacetic acid which are eliminated with the urine. Up to now, it has not been ascertained whether the oxirane ...

A Box-Behnken design with three replicates was used for preparation and evaluation of Eudragit vancomycin (VCM) nanoparticles prepared by double emulsion. The purpose of this work was to optimize VCM nanoparticles to improve the physicochemical properties. Nanoparticles were formed by using W1/O/W2 double-emulsion solvent evaporation method using Eudragit RS as a retardant material. Full factor...

Cellular manufacturing (CM) is one of the most important subfields in the design of manufacturing systems and as a recently emerged field of study and practice, virtual cellular manufacturing (VCM) inherits the importance from CM. One type of VCM problems is VCM with alternative processing routes from which the route for processing each part should be selected. In this research, a bi-objective ...

Voice coil motor (VCM) is a special direct drive linear motor, which can convert electric energy directly into mechanical without the use of transmission mechanism. VCM has advantages simple structure, good rigidity, fast response, silence, high linearity, no cogging force, pulsation et al. It widely used in field high-precision control. This paper reviews and summarizes results research conduc...

Vinyl chloride (VCM) induced angiosarcoma of the liver (ASL) is a rare vascular tumor which might be associated with a wide range of disease states. The possibility that this tumor might be a signal lesion is supported by mortality studies suggesting that cancers of the digestive, respiratory, neurological and lymphatic systems have occurred more often than expected in VCM workers. There is als...

In this paper, we propose a new agent-based flexible videoconference system (AVCS) by modifying videoconference manger (VCM) agent in a conventional flexible videoconference system (FVCS). The proposed AVCS can more flexibly cope with changes in working conditions during videoconferencing than the conventional FVCS. It is because an automatic parameter tuning algorithm is imbedded to VCM dynami...