Sinkler SY, Segal SS. Aging alters reactivity of microvascular resistance networks in mouse gluteus maximus muscle. Am J Physiol Heart Circ Physiol 307: H830–H839, 2014. First published July 11, 2014; doi:10.1152/ajpheart.00368.2014.—Aging occurs with enhanced sympathetic nerve activity and endothelial dysfunction; however, little is known of how successive branches of microvascular resistance ...

The present study was designed to determine the effect of recombinant inducible nitric oxide (NO) synthase (iNOS) gene expression on vasomotor function in cerebral arteries. Isolated canine basilar arteries were exposed ex vivo (30 min at 37 degrees C) to an adenoviral vector [10(7), 10(8), or 10(9) plaque-forming units (pfu)/ml] encoding either the iNOS gene or the beta-galactosidase reporter ...

Book Reviews E. TROSTDORF, H. STENDER (ed.): Wirbelsaule und Nervensystem. Thieme, Stuttgart 1970. VIII + 208 pp., 127 fig., 21 tab. DM 49.-. This is a comprehensive monograph on degenerative, traumatic and inflammatory diseases of the vertebral column. Morphological and physiological aspects, biomechanical problems, X-rays, myelography, spinal scintigraphy, malformations, lumbar and cervical d...

BACKGROUND Familial dysautonomia (FD) is a rare hereditary disease characterized by loss of afferent autonomic neural fiber signaling and consequent profound impairment of arterial baroreflex function and blood pressure regulation. Whether vascular endothelial dysfunction contributes to defective vasomotor control in this form of afferent autonomic failure is not known. METHODS We assessed bl...

The diagnosis of intracranial stenosis has improved with the advent and availability of non-invasive vascular imaging tests. Vascular imaging modalities to consider include transcranial Doppler, magnetic resonance and computed tomographic angiography. While these have strengths and weaknesses, they provide anatomic information. Physiologic and/or hemodynamic data can be gleaned from perfusion i...