Background: Vaginitis means inflammation of the vaginal mucosa and is one most common causes for consulting to a gynecologists. Mixed-type infections are simultaneous at least two types pathogens (for example, bacteria Candida species). In treatment mixed vaginitis, broad spectrum antimicrobial therapy effective on different kinds required. Aim: The purpose this review evaluate place efficacy f...

UNLABELLED Vaginal inflammation (vaginitis) is the most common disease caused by the human-pathogenic fungus Candida albicans. Secretory aspartyl proteinases (Sap) are major virulence traits of C. albicans that have been suggested to play a role in vaginitis. To dissect the mechanisms by which Sap play this role, Sap2, a dominantly expressed member of the Sap family and a putative constituent o...

Sera from 200 pregnant women, with symptoms suggestive of vaginitis and harbouring yeast in the vagina, were examined for precipitating antibodies to three antigens of C. albicans, using a gel double diffusion test. A high overall incidence of precipitin-positive sera (47.5%) was found compared with an incidence of 18% in the unselected pregnant population previously studied (Stanley, Hurley, a...

BACKGROUND AND OBJECTIVES Vulvovaginal candidiasis is a common fungal infection among women during reproductive ages. Although, Candida albicans is accounted as the main etiologic agent of vaginitis, non-albicans species have arisen during last years. Resistant to antifungal drugs especially, fluconazole has been more reported by researchers from around the World. The aims of this study were to...

We compared susceptibility to Candida vaginitis in derived murine substrains differing in sensitivity to estrogen (CD-1 and CD10, resistant; CD3 and C57BL/6 responsive), and in F1 crosses. The order of decreasing resistance was CD-1 > or = CD10 > or = CD10 x CD3F1 > CD10 x B6F1 > CD3 > C57BL/6 and correlated with estrogen responsiveness in endocrine disruptor assays. Resistance to Candida vagin...

SYNOPSIS Sera from 200 pregnant women, with symptoms suggestive of vaginitis and harbouring yeast in the vagina, were examined for precipitating antibodies to three antigens of C. albicans, using a gel double diffusion test. A high overall incidence of precipitin-positive sera (47.5 %) was found compared with an incidence of 18% in the unselected pregnant population previously studied (Stanley,...

Vaginitis is mostly caused by Trichomonas vaginalis leading to mild to severe infections in the vaginal mucosa. The treatment for this disease can be initiated with the help of antimicrobial and antifungal agents in various dosage forms. Novel dosage forms have gained prior significance in recent formulation researches due to their inevitable controlled drug release mechanism and site specific ...

INTRODUCTION Infectious vaginitis is a common clinical syndrome diagnosed in more than one quarter of women attending clinics for sexually transmitted diseases (STDs) [1] and with increasing frequency in private practice [2]. Effective management of the syndrome depends on an acceptably accurate etiologic diagnosis, as the most effective therapies are narrowspectrum medications that target the ...