Automatic identification of anomalies on network data is a problem of fundamental interest to ISPs to diagnose incipient problems in their networks. ISPs gather diverse data sources from the network for monitoring, diagnostics or provisioning tasks. Finding anomalies in this data is a huge challenge due to the volume of the data collected, the number and diversity of data sources and the divers...

In this paper, we present a novel meta-heuristic technique for the nurse scheduling problem (NSP). This well-known scheduling problem assigns nurses to shifts per day taking both hard and soft constraints into account. The objective is to maximize the preferences of the nurses and to minimize the total penalty cost from violations of the soft constraints. The problem is known to be NP-hard. Due...

Xin L, Hyldahl RD, Chipkin SR, Clarkson PM. A contralateral repeated bout effect attenuates induction of NFB DNA binding following eccentric exercise. J Appl Physiol 116: 1473–1480, 2013. First published August 15, 2013; doi:10.1152/japplphysiol.00133.2013.—We investigated the existence of contralateral repeated bout effect and tested if the attenuation of nuclear factor-kappa B (NFB; an import...

The time course for the activation of glycogen phosphorylase (Phos) and pyruvate dehydrogenase (PDH) and their allosteric regulators was determined in human skeletal muscle during repeated bouts of maximal exercise. Six subjects completed three 30-s bouts of maximal isokinetic cycling separated by 4-min recovery periods. Muscle biopsies were taken at rest and at 6, 15, and 30 s of exercise duri...

The government's Public Health White Paper for England sets out a utopian vision of how to prevent and remedy mental health problems. The public health approach relies on primary prevention, promoting individual responsibilities and resilience, while also sustaining existing services and tackling inequalities. These ambitions are consistent with the preventive psychiatric paradigm, and with the...

Abstract Utopian images in XR-games are often ambiguous. How can ambiguity be consciously designed virtual worlds? What the design principles for game designers? Ambiguity arises from discontinuity and decontextualization, deliberate omission of facts, skillful superimposition contradictory codes. An ontology interactive media explains elusive visual poetry image perception. The five basic elem...