Aplastic Anemia 11-18 Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppression treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation Anna Locasciulli, Rosi Oneto, Andrea Bacigalupo, Gerard Socié, Elisabeth Korthof, Albert Bekassy, Hubert Schrezenmeier, Jakob Passweg, Monika Führer, on the be...

Introduction: The use of cord stem cells, as a cell source for bone marrow reconstruction in patient under hematopoietic stem cell transplantation is enhancing. The amount of CD34+cells collected from cord blood compared to peripheral blood and bone marrow are less, but their collectionprocesure is easier. Delay in freezing has negative effect on cells surveillance and reduce their ability in ...

Failure of revascularization is known to be the major reason for the poor outcome of pancreatic islet transplantation. In this study, we analyzed whether pseudoislets composed of islet cells and bone marrow cells can improve vascularization and function of islet transplants. Pancreatic islets isolated from Syrian golden hamsters were dispersed into single cells for the generation of pseudoislet...

background: during the resent years there has been interest in using bone marrow stem cells to treat liver cirrhosis. however, there is a potential concern for malignant transformation after stem cell therapy. the aim of this study was to evaluate the development of hepatocellular carcinoma (hcc) after autologous bone marrow stem cell transplantation for liver cirrhosis. methods: all the patien...

To identify cells with potential antileukemia activity following bone marrow transplantation. we have monitored immunologic reconstitution in a patient with acute lymphocytic leukemia in second remission who received intensive chemotherapy and total body irradiation followed by infusion of albogeneic histocompatible marrow. Prior to transplantation. donor bone marrow cells were depleted of T ly...

Bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord of rats with ischemia/reperfusion injury. Although bone marrow mesenchymal stem cells are known to protect against spinal cord ischemia/reperfusion injury through anti-apoptotic effects, the precise mechanisms remain unclear. In the present study, bone marrow mesenchymal ste...