Background & Aims: Tyrosinase is the most important enzyme in the production of pigments of the skin, eyes, and hair follicles. The enzyme is encoded by tyrosinase gene (TYR) or oculocutaneous albinism type 1A (OCA1A). Mutations in TYR gene result in pigmentation disorders such as albinism in humans. In view of the large number of mutations reported in this gene, the aim of this study was to id...

background: cholangiocarcinoma is an invasive biliary malignancy with poor prognosis. diagnostic accuracy of conventional methods is low which is mainly due to the specific anatomy of the disease. the aim of this study was to evaluate the diagnostic value of biochemical profile and tumor marker of the bile in patients with malignant cholestasis compared to that of choledocholithiasis. methods: ...

introduction: about one third of the world's population is infected with tuberculosis (tb) and each year, about 1.5 to 2 million people die from tb. procalcitonin (pct) is an inflammatory marker that its level has variable materials and methods: this conducted on patients with pulmonary tb. data were collected using a check list. the serum level of pct was measured by elisa test at the beg...

background and objective: in this study, we explored expression rate, some biomarkers affecting the prognosis of the breast carcinoma, and the relationship between these markers and clinicopathologic features of the disease as well as the relationship between each of these markers through a tissue array technique. materials and methods: this study was an observational and cross-sectional study....

genomic selection is a method to predict the breeding values of individuals using a large number of single nucleotide polymorphism markers. the cost of the high-density marker panel genotyping is very high, which prevents the widely application of genomic selection. the present simulation study was carried out to evaluate the use of low to medium marker density panels to predict direct genomic ...

genetic markers are one of the advances which have occured in the genomics era. among genetic markers, molecular markers mainly because of their abundance, are the most widely used them. development of molecular markers has greatly altered genetics and plant breeding. genetic markers indicate the genetic differences between different organs or species. some studies which were conducted during t...