OBJECTIVE To assess the efficacy and safety of duloxetine in women with stress urinary incontinence. DESIGN Randomised double-blind, placebo-controlled clinical trial. SETTING Fort-six centres in seven European countries and Canada. POPULATION Four hundred and ninety-four women aged 24-83 years identified as having predominant symptoms of stress urinary incontinence using a clinical algor...

PURPOSE We quantified and described the economic burden of overactive bladder and stress urinary incontinence in Korea. We calculated direct costs by identifying public and private data sources that contain population-based data on resource utilization by patients with stress urinary incontinence and overactive bladder. METHODS For estimating indirect costs (productivity loss), the human capi...

BACKGROUND Electrical stimulation is commonly recommended to treat urinary incontinence in women. It includes several techniques that can be used to improve stress, urge, and mixed symptoms. However, the magnitude of the alleged benefits is not completely established. OBJECTIVES To determine the effects of electrical stimulation in women with symptoms or urodynamic diagnoses of stress, urge, ...

There is insufficient data to assess the effects of any different management strategies for recurrent or persistent stress urinary incontinence in women after failed interventional treatment. The evidence base lacks well-designed randomised trials with sufficient power answer this hugely important issue. PURSUIT Proper Understanding Recurrent Stress Urinary Incontinence Treatment study, assessi...

Stress urinary incontinence is the complaint of involuntary leakage of urine on effort or exertion, or on sneezing or coughing. In urodynamic terms, stress continence is maintained when the maximum urethral pressure exceeds the intravesical pressure. In the McGuire classification system, type 1 and 2 stress incontinence occur because of urethral hypermobility and type 3 because of intrinsic sph...

Urinary incontinence is a common condition affecting 20 to 40% of older women.1 The two most common types of urinary incontinence are stress incontinence, the involuntary loss of urine resulting from increased abdominal pressures (such as with a cough or Valsalva’s maneuver), and urge incontinence, the involuntary loss of urine after an unwanted contraction of the detrusor muscle.2 Some patient...

In women, stress urinary incontinence is a common problem that may lead to sexual dysfunction. We review the epidemiological data, the pathophysiology, and the risk factors for these two "closet" disorders, how they are related, how we can get patients to talk about them, and how the treatment of stress urinary incontinence may affect sexual dysfunction.