During a routine visit for nail care and diabetic neuropathy evaluation, laboratory tests were ordered for a 64-year-old man with a history of diabetes mellitus and hypertension. At the time, he had no symptoms of any acute problem. A serum separator tube was received and revealed sodium 162 mmol/L, potassium 3.8 mmol/L, chloride 88 mmol/L, CO2 20 mmol/L, and anion gap 54 mmol/L with normal blo...

Acute kidney injury (AKI) resulting from ischemia-reperfusion (IRI) is among the most common complications in hospitalized patients. In recent years, it has been argued that exercise an approach to attenuate impairments caused by AKI. The purpose of this study was investigate whether eight weeks resistance training (RT) protective effects on IRI. Thirty male Wistar rats (210-230 g) were randoml...

Abstract To investigate the effect of pomegranate juice (PJ) on cyclosporine (CsA)-induced nephrotoxicity in rats, 80 rats were divided into four groups. The first group was regarded a negative control group, and others as follows: 2 (CsA group) received CsA dose 25 mg/kg/day orally, 3 (treated plus 2.5 mL/day PJ, 4 (PJ mL PJ daily. By end 21st day, plasma creatinine, blood urea nitrogen (BUN),...

We report results of a 21-week evaluation of an engineering model of the Kodak “EKTACHEM Glu/BUN Analyzer.” This novel clinical instrument measures glucose and “urea nitrogen” (actually, urea) in a minimum of 30 j.tL of body fluids by use of the principles of thin, multilayer film analysis and reflectance spectrophotometry. We compared the performance of the instrument to that of the Dupont aca...

Associations between the presence of a constitutional variant of delta-aminolevulinic acid dehydratase (ALAD-2) and lead concentrations in blood and bone, as well as between this allele and indices of kidney function, were investigated among 691 members of a construction trade union. The average blood lead level in this group was 7.78 micrograms/dl. No significant difference was observed in blo...

Abbreviations: FUO: Fever of Unknown Origin; VAP: Ventilator Associated Pneumonia; SpO2: Oxygen Saturation; TLC: Total leukocyte Count; ESR: Erythrocyte Sedimentation Rate; BUN: Blood Urea Nitrogen; TB-PCR: Tuberculosis Polymerase Chain Reaction Test; CT Neck: Computed Tomography; D2 level: 2nd Post Cervical Spinal Segment; C4 vertebra: 4th Cervical Vertebra; TPN: Total Parenteral Nutrition; Ac...

A 63-year-old woman is admitted to the hospital with acute pancreatitis of presumed biliary origin. Laboratory results include white blood cell count (WBC) 18,500; hemoglobin 13.0; platelets 191,000; alanine aminotransferase (ALT) 330; aspartate aminotransferase (AST) 260; alkaline phosphatase 250; bilirubin 1.4; glucose 225; blood urea nitrogen (BUN) 47; creatinine 1.4; and prothrombin time 12...

Among critically ill patients, acute kidney injury (AKI) is a relatively common complication that is associated with an increased risk for death and other complications. To date, no treatment has been developed to prevent or attenuate established AKI. Dialysis often is required, but the optimal timing of initiation of dialysis is unknown. Data from the Program to Improve Care in Acute Renal Dis...

The effect of cystone, a polyherbal ayurvedic preparation, on the nephrotoxicity and antitumor activity of cisplatin is studied in C57BL/6J mice bearing B16F1 melanoma. Intraperitoneal administration of cisplatin 6 mg/kg, resulted in significant reduction of body weight, elevation of blood urea nitrogen (BUN) and serum creatinine levels on day 5. Cystone was found to protect tumor-bearing mice ...

The most frequent laboratory abnormalities in patients with congenital portosystemic shunts (CPSS) are microcytosis, hypoglycemia, hypoalbuminemia, hypoproteinemia, increased liver enzyme activities, decreased blood urea nitrogen (BUN) and urate crystalluria. The microcytosis is probably due to impaired iron transport. Hypoglycemia, hypoalbuminemia, hypoproteinemia and decreased BUN are partly ...