To utilize the rat spinotrapezius muscle as a model to investigate the microcirculatory consequences of exercise training, it is necessary to design an exercise protocol that recruits this muscle. There is evidence that the spinotrapezius is derecruited during standard treadmill exercise protocols performed on the uphill treadmill (i.e., 6 degrees incline). This investigation tested the hypothe...

OBJECTIVE To study adjustment strategies in unilateral amputees in uphill and downhill walking. DESIGN Observational cohort study. SUBJECTS Seven transfemoral, 12 transtibial unilateral amputees and 10 able-bodied subjects. METHODS In a motion analysis laboratory the subjects walked over a level surface and an uphill and downhill slope. Gait velocity and lower limb joint angles were measu...

Mechanical loading of tissue is known to influence local collagen synthesis, and microdialysis studies indicate that mechanical loading of human tendon during exercise elevates tendinous type I collagen production. Transforming growth factor-beta1 (TGF-beta1), a potent stimulator of type I collagen synthesis, is released from cultured tendon fibroblasts in response to mechanical loading. Thus T...

The aim of this study was to quantify and describe the exercise intensity of ski mountaineering racing, and to identify the best physiological predictors of ski mountaineering racing. Before participating in the race in which heart rate (HR) and speed were continuously recorded, 10 trained ski-mountaineers performed a field maximal test to determine the first ventilatory threshold (VT1) and the...

Dinaric Alps: the other Alps. They still give off that vibe, don’t they? The entire region: Europe. We will probably never shake attribute, so why not embrace it? If Balkan region is Europe, then Alps are other, darker, unknown, chaotic Alps? Let’s pretend, for sake of this article, they are. A large part Bosnia and Herzegovina eponymous mountain – Dinara, lie within range. Apart from extreme n...

This study aimed to compare the muscle activities of the lower limb during overground level running (LR) and uphill running (UR) by using a musculoskeletal model. Six male distance runners ran at three running speeds (slow: 3.3 m/s; medium: 4.2 m/s; and high: 5.0 m/s) on a level runway and a slope of 9.1% grade in which force platforms were mounted. A musculoskeletal leg model and optimization ...

The human gluteus maximus is a distinctive muscle in terms of size, anatomy and function compared to apes and other non-human primates. Here we employ electromyographic and kinematic analyses of human subjects to test the hypothesis that the human gluteus maximus plays a more important role in running than walking. The results indicate that the gluteus maximus is mostly quiescent with low level...

PURPOSE Recent evidence suggests that regular exercise training plays a decisive role in maintaining homeostasis and promoting muscle and skeletal formation. However, the effect of downhill exercise training on osteogenesis-related factors is not well understood. METHODS Thus, we investigated the effect of uphill and downhill training on ovariectomy (OVX)-induced bone loss. After ovary remova...