BACKGROUND AND OBJECTIVE Tube feeding has been significantly associated with a higher rate of aspiration pneumonia that is mainly related to oral microorganisms and a reduced salivary flow. Thus, the difference in the mode of nutritional intake is expected to affect the oral environment, but this has not yet been fully clarified. The purpose of this study was to investigate, in tube-fed patient...

The soluble urokinase plasminogen activator receptor (suPAR) has been detected in blood, plasma, serum, urine, ovarian cystic fluid, and cerebrospinal fluid. Elevated suPAR levels in plasma have been associated with negative outcomes in various diseases, such as bacteremia, sepsis, SIRS, cardiovascular disease, cancer, and tuberculosis. The primary aim of this study was to investigate whether s...

OBJECTIVES (1) To estimate the prevalence of ocular and oral sicca symptoms (SISY) or reduced saliva and tear production; (2) to relate SISY and sicca signs to measures of disease activity, damage, and health status; and (3) to examine the relation between symptoms and objective signs of tear and saliva production in a large sample of representative patients with rheumatoid arthritis (RA). ME...

introduction xerostomia is one of side-effects of radiotherapy for head and neck cancers. no definitive method has been proposed for the treatment of this condition. however, pilocarpine is considered effective for the management of chronic xerostomia. the purpose of the present study was to assess the preventive effect of pilocarpine. materials and methods this study was performed on 34 patien...

background: infl ammatory cytokines such as interleukin-6 (il-6) and tumor necrosis factor-alpha (tnf-α) are elevated in end-stage renal disease (esrd). il-6 and tnf-α are toxins which deteriorate renal function, and their pathogenic role has been confi rmed in cardiovascular and oral diseases. this study was designed to investigate the salivary levels of il-6 and tnf-α in patients with esrd un...

OBJECTIVE The aim of the current study was to carry out a preliminary validation of devices for standardized collection of whole mouth fluid (WMF) in comparison to the passive drooling method for protein analysis in healthy subjects. MATERIALS AND METHODS A carefully designed sample collection/pretreatment protocol is crucial to the success of any saliva proteomics project. In this study, WMF...

Saliva is secreted into the mouth at a rate of 0.3 to 0.4 ml per minute. Retained saliva in the mouth physiologically triggers swallowing to carry the saliva out of the mouth. Dawes (1983) have reported the volume of saliva in the mouth just before swallowing, the rate of swallowing, the volume swallowed per swallow, and the volume of saliva in the mouth just after swallowing. Clearance of mate...