Stretching before performance is a common practice among athletes in hopes of increasing performance and reducing the risk of injury. However, cumulative results indicate a negative impact of static stretching and proprioceptive neuromuscular facilitation (PNF) on performance; thus, there is a need for evaluating other stretching strategies for effective warm-up. The purpose of this study was t...

A deep inspiration (DI) temporarily relaxes agonist-constricted airways in normal subjects, but in asthma airways are refractory and may rapidly renarrow, possibly due to changes in the structure and function of airway smooth muscle (ASM). Chronic largely uniaxial cyclic strain of ASM cells in culture causes several structural and functional changes in ASM similar to that in asthma, including i...

The rheological behaviour of polymer melts and dilute polymer solutions in elongational flow have been extensively examined through experiments and theoretical predictions. However, an experimental study to understand the extensional rheological properties of polymer solutions in the semi-dilute regime is currently lacking in terms of a systematic examination of the effects of concentration and...

We examined the effects of mechanical forces on actin polymerization at focal adhesions (FAs). Actin polymerization at FAs was assessed by introducing fluorescence-labeled actin molecules into permeabilized fibroblasts cultured on fibronectin. When cell contractility was inhibited by the myosin-II inhibitor blebbistatin, actin polymerization at FAs was diminished, whereas alpha(5)beta(1) integr...

The functionalization of nanoporous ceramics for applications in healthcare and defence necessitates the study effects geometric structures on their fundamental mechanical properties. However, there is a lack research stiffness fracture strength along diverse directions under multi-axial loading conditions, particularly with existence typical voids models. In this study, accurate atomic models ...

Thermoplastic elastomer/carbon nanotube composites are studied for sensor applications due to their excellent mechanical and electrical properties. Piezoresisitive properties of tri-block copolymer styrene-butadiene-styrene (SBS)/ carbon nanotubes (CNT) prepared by solution casting have been investigated. Young modulus of the SBS/CNT composites increases with the amount of CNT filler content pr...

Several studies utilizing adult subjects have indicated that static stretching may reduce subsequent strength and power production, possibly for as long as an hour following the stretch. This observation has not been evaluated in children, nor in athletes accustomed to performing static stretches during strength/ power type training sessions. The purpose of this investigation was to determine i...

Tensile forces generated by stress fibers drive signal transduction events at focal adhesions. Here, we report that stress fibers per se act as a platform for tension-induced activation of biochemical signals. The MAP kinase, ERK is activated on stress fibers in a myosin II-dependent manner. In myosin II-inhibited cells, uniaxial stretching of cell adhesion substrates restores ERK activation on...