We describe a case of a 32-year-old patient with ulcerative colitis complicated by Hodgkin s disease who presented with nephrotic syndrome. The patient had suffered from relapsing ulcerative colitis for 6 years before he developed Hodgkin s lymphoma. He was treated for Hodgkin s disease with 9 cycles of combined chemotherapy (COPP/ABV) and achieved the stabile remission of lymphoma, nephrotic s...

This report describes a young woman with ulcerative colitis who developed rapidly fatal pneumococcal septicaemia. Necropsy revealed splenic atrophy. This case supports the hypothesis that splenic atrophy might contribute to the morbidity of ulcerative colitis. The occurrence of splenic atrophy in ulcerative colitis is now well established. Splenic atrophy from other causes has been associated w...

OBJECTIVE To investigate whether cochlear involvement is an extraintestinal manifestation in patients with ulcerative colitis. METHOD Forty-four ulcerative colitis patients and 44 age-matched healthy subjects were included in the study. Pure tone and speech audiometry, and distortion product otoacoustic emission tests were performed on all participants. The audiometric test results were compa...

Lysozyme (LZM) was identified in ulcerative colitis in granulocytes, monocytes, and macrophages of the intestinal lamina propria. In contrast with findings in normal colon or rectum, in ulcerative colitis LZM was also detected in some mucosal crypt cells and metaplastic Paneth cells. In both ulcerative colitis and Crohn's disease LZM was present in inflammatory cells of crypt abscesses. In Croh...

Ulcerative colitis is an inflammatory bowel disease of uncertain etiology with recurrent symptoms and considerable morbidity. There is no known medical cure for ulcerative colitis. The ultimate goal of treatment in any patient suffering from ulcerative colitis is inducing and maintaining clinical remission. New uses are being found for old drugs, and more and more new drugs are becoming availab...

introduction: ulcerative colitis (uc) is a chronic inflammatory disorder of the colon of unknown cause that is associated with important nutrition deficiencies such as protein-energy malnutrition, vitamin and mineral deficiencies. because no study has been carried out to date in iran, the aim of this pilot study was the assessment of dietary intake of these patients. methods: in this pilot stud...

conclusions this study showed the importance of considering syndrome differentiation and temperaments in interpreting the effect of p. granatum peels extract on ulcerative colitis. results therapeutic response was significantly higher in patients with hot temperament compared to patients with cold temperament in the p. granatum group (1.916 ± 0.492 versus -0.500 ± 0.500, p = 0.029). methods sev...

BACKGROUND More than two-thirds of ulcerative colitis patients experience at least one relapse over a period of 10 years. Treatments that reduce the likelihood of relapses also reduce the risk of long-term complications. AIM To review three topics: the current standard of treatment for ulcerative colitis, evolving concepts in treatment, and disease modification as a treatment goal of the futu...

The incidence of lactose malabsorption was investigated in 85 patients with ulcerative colitis and 71 patients with Crohn's disease by means of lactose tolerance tests and disaccharidase determinations in small intestinal mucosa. Eight patients with ulcerative colitis (9%) and four with Crohn's disease (6 %) had lactose malabsorption. A control group displayed a similar incidence. It is conclud...

AIMS To study ulcerative colitis associated neutrophil cytoplasmic antibodies (p-ANCA) in respect of class and subclass distribution, antigen specificity, and (sub)cellular localisation of the antigen(s) to which these antibodies are directed. METHODS p-ANCA positivity was determined using the standard indirect immunofluorescence test (IIFT). The immunoglobulin (Ig) subclass distribution of p...