The influence of the age of onset of symptoms on various clinical features of peptic ulcer was studied in a personal series of 492 patients (duodenal ulcer 363, gastric ulcer 98, combined gastric and duodenal ulcer 31). Duodenal ulcer patients whose age of onset of symptoms was within the first three decades (n = 166) were more likely to be men (77%) and to have a positive family history of dys...

498 British Journal of General Practice, September 2013 INTRODUCTION The word dyspepsia derives its origin from the Greek work dyspeptos, which means ‘bad digestion’. The term is used to describe symptoms thought to be referable to the upper gastrointestinal (GI) tract. Which symptoms to include in the definition of dyspepsia is controversial, but upper abdominal pain or discomfort, bloating, f...

Patients taking anti-inflammatory drugs for arthritis are prone to dyspepsia, and management of peptic ulcer is difficult because surgery is poorly tolerated. In this open study cimetidine treatment was associated with ulcer healing in 17 out of 21 patients with arthritis even when anti-inflammatory treatment was continued. Remission was maintained for 1 year by continued cimetidine therapy.

OBJECTIVE To assess prevalence of dyspepsia and distribution of dyspepsia and frequent dyspepsia in subgroups of adults (20 years and older) according to their demographic and socioeconomic characteristics. METHODS A cross-sectional population-based study was carried out comprising 3,934 subjects living in Pelotas, Southern Brazil, from October 1999 to January 2000. Data was collected through...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1327 toms in 90 percent of infected persons. The prevalence of H. pylori infection varies geographically and has been demonstrated to be as high as 52 percent in the United States. Factors associated with higher infection rates are increasing age, African-American or Hispanic race, lower levels of education, and birth in a developing country. The patho...

Antibody titres to Campylobacter pyloridis in serum and gastric juice were estimated by an enzyme linked immunosorbent assay (ELISA) to whole organisms obtained from bacterial culture in 39 patients with non-ulcer dyspepsia. Whereas 20 of the 21 patients with chronic gastritis had gastric C pyloridis, 17 patients with no Cpyloridis had normal histology in the gastric antrum and body. Significan...

BACKGROUND Helicobacter-pylori-related duodenal ulcer (DU) is an important cause of dyspepsia. AIM To determine the relationship between the pattern of H. pylori infection and the epidemiology of duodenal ulcer in a single population. DESIGN Prospective two-part study of (i) patients with DU referred for endoscopy because of dyspepsia, and (ii) the incidence of H. pylori infection in the ge...

The occurrence of peptic ulcer increased rapidly in all Western countries from the 19th to the 20th century, attributed to a possible epidemic of Helicobacter pylori, a new pathogenic strain, or a change in host susceptibility. The early trends in hospital admissions for peptic ulcer and dyspepsia in London and New York during the 19th century are reviewed to test these hypotheses.

background : data concerning the information on the prevalence and association of the helicobacter pylori cytotoxinassociated gene a (caga) with disease is still controversial. the aim of this study was to isolate and identify h. pylori by culture methode from biopsy specimens and its relationship with associated diseases by molecular techniques (pcr). materials and methods: gastric biopsy spec...

A survey of recurrent indigestion in four general practices (19,619 patients) showed a wide range of dyspeptic complaints. Of these 82 (4.2 per 1,000) already had a proved ulcer and 144 (7.3 per 1,000) had symptoms suggesting a duodenal ulcer and had either not been investigated or had previously had a normal barium meal. A duodenal ulcer was found radiologically in half the men (46 out of 95) ...