نتایج جستجو برای: tyrosine kinase inhibitor

تعداد نتایج: 426607  

Journal: :Canadian journal of health technologies 2022


 CADTH recommends that Rozlytrek be reimbursed by public drug plans for the treatment of adults with unresectable locally advanced or metastatic extracranial solid tumours, including brain metastases, have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion without known acquired resistance mutation if certain conditions are met.
 should only to treat patients who previously f...

Journal: :Journal of Pharmaceutical Negative Results 2022

Introduction: chronic myeloid leukemia is one of the major diseases, which cause death worldwide. Tyrosine kinase responsible for uncontrolled cell growth and block its function. Its inhibition a promising route to control out grow cells. The purpose our study involves docking human Abl with seven ciprofloxacin derivatives comparison results free energy binding positive (Imatinib).Methods: pres...

Journal: :European Journal of Medicinal Chemistry 2019

2017
Inge G.P. Geelen Noortje Thielen Jeroen J.W.M. Janssen Mels Hoogendoorn Tanja J.A. Roosma Sten P. Willemsen Otto Visser Jan J. Cornelissen Peter E. Westerweel

Evaluations of the 'real-world' efficacy and safety of tyrosine kinase inhibitors in patients with chronic myeloid leukemia are scarce. A nationwide, population-based, chronic myeloid leukemia registry was analyzed to evaluate (deep) response rates to first and subsequent treatment lines and eligibility for a treatment cessation attempt in adults diagnosed between January 2008 and April 2013 in...

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