Zataria multiflora Boiss. is used in Iranian traditional medicine to treat gastrointestinal disorders and menrrhalgia. The inhibitory effect of this herb on rat ileum contractions is also reported. The aim of this study was to investigate the effect of Zataria multiflora Boiss. hydroalcoholic leaf extract (ZHLE) on isolated rat uterus in presence of some known uterus stimulants. Pieces of virgi...

introduction: there have been many studies in recent years on the role of nitric oxide (no) in acute renal failure. in this study, the effects of inhibition or interoduction of no synthase on renal toxicity of gentamicin were investegated. materials & methods: isolated kidneys of male rats were perfused with tyrode buffer (t) as the control group, t+l-argrinine as group 2, t+l-name as group 3, ...

The effects of mefloquine on the mechanical activity of the mouse isolated rectal smooth muscle was studied. Mefloquine (4.1 x 10(-5) - 5.2 x 10(-3)M) when applied alone and separately exerted variable effects on the rectum. In some preparations, it caused slight phasic contractions while in others no response was elicited. When the external Ca(2+) was increased from 1.8 mM to 300 mM mefloquine...

1. In a search for suitable tissues for the cultivation of yellow fever virus in vitro, mouse embryos were inoculated with this virus in utero. A titration for virus content of the various organs of the embryos indicated that the virus was present in the brain in greatest concentration. 2. Unmodified strains of yellow fever virus were readily adapted to cultivation in vitro in a medium consisti...

In order to improve the effectiveness of a previously described1),2) isolated guinea-pig lung technique, the apparatus was redeveloped and modifications were introduced. The artificial thorax volume has been reduced considerably and air conditioning adopted instead of waterbath heating. The cover-plate is equipped with a calibrated orifice, magnetic locking and pass-through electrodes for vagal...

We examined the possible role of the Na-Ca exchange (NCX) in the arrhythmogenesis in rat atrial preparations applying microelectrode technique. In control Tyrode solution preparations isolated from the sinoatrial area contracted with frequency of 48+/-4 min(-1) (group I) or 84+/-7 min(-1) (group II). In preparation beating with low frequency partial inhibition of NCX by administration of Ni2+ (...

With the use of a nonsensitized segment serving as indicator, the release of histamine or other substances during anaphylactic contraction in the isolated sensitized guinea-pig ileum was demonstrated (1). Histamine release in anaphylaxis was measured by immersing sensitized guinea-pig tissues including the small intestine in Tyrode solution containing the antigen (2,3). Attempts to demonstrate ...

A strain of lymphocytic choriomeningitis virus has been encountered, which grows readily in mouse embryo, serum, Tyrode culture media. Its origin is not definitely known but appears to be either the mouse brain tissue or, more probably, the monkey serum. This strain gives clear cut results on filtration tests through Elford membranes, establishing the size of the virus, according to formula, as...

In 1953, Bülbring noted that the smooth muscle of teania coli from guinea pig showed an increase in oxygen consumption associated with tension development when stimulated by a drug such as acetylcholine, histamine or eserine (1). Recently Urakawa and his co workers found that high concentration of potassium in Tyrode solution induced an in crease in oxygen consumption accompanied by a rise...