We describe a variant of typhoid which was clinically indistinguishable from Japanese Encephalitis (JE). The strongly encephalitic presentation led to a potentially serious delay in starting specific antibiotic therapy. Awareness of the usual form of typhoid is of great importance to Army doctors because of the presence of British soldiers and families in the Dharan area of southern Nepal where...

Salmonella enterica subspecies enterica serotype Typhi (S. Typhi) is the causative agent of typhoid fever that is still a major challenge for public health in developing countries. The bacterium is transmitted by faeco-oral route, through contaminated water or food. Salmonella Typhi is highly adapted to human host; the only reservoir is man. The diagnosis of typhoid becomes difficult as discrim...

In 1835 Maisonneuve first recognized osteomyelitis as a complication of typhoid and since then this bone lesion, although well known, has been reported only occasionally. Murphy (1916) collected 164 cases of typhoid periostitis and osteitis occurring in 18,840 cases of typhoid infection reported by 15 authors, an incidence of 0 82% of bone involvement. Veal (1939) also found osteitis in less th...

A case of typhus fever is presented. On admission, the clinical diagnosis was typhoid fever. Forty-eight hours after admission, the presence of subconjunctival haemorrhage, malena, and jaundice raised the possibility of a different aetiology, the two most likely differentials being dengue and typhus. Finally, a co-infection of typhoid and typhus was discovered. This uncommon clinical scenario s...

Typhoid fever being a systemic infection can present in a multitude of ways, involving various systems. Here we describe a case of typhoid fever presenting with acute cerebellar ataxia and marked thrombocytopenia. This atypical presentation is not common in typhoid fever and can lead to misdiagnosis as well as a delay in the initiation of appropriate therapy. Prompt clinical improvement and the...

It is only of late years that enteric fever was known to exist in India, and, since its discovery, it lias become too much the fashion to call by the name of " typhoid" every case of continued fever lasting more than four or five days, setting down the absence of nil and every characteristic symptom of typhoid to modification by climate. Nearly all the cases hitherto reported have occurred in E...

Typhoid fever is a systemic prolonged febrile illness caused by a bacteria Salmonella typhi. The disease is transmitted through ingestion of food or water contaminated with faeces or urine of infected persons. Acute typhoid fever is characterized by prolonged fever, disturbances of bowel functions (constipation or diarrhoea), headache, malaise and anorexia. Cough is common in the early stage of...

BACKGROUND & OBJECTIVES Malaria and typhoid fever still remain diseases of major public health importance in the tropics. Individuals in areas endemic for both the diseases are at substantial risk of contracting both these diseases, either concurrently or an acute infection superimposed on a chronic one. The objective of this report was to systematically review scientific data from studies cond...

A laboratory study was carried out on 44 sera of typhoid patients (age: 15-45 years, 24 females and 20 males) with positive blood culture for S. typhi, 41 sera non typhoid febrile patients (age: 16-51 years, 17 females & 24 males) with negative blood culture and negative Widal test, 136 sera of healthy persons as normal controls (age: 20-49 years, 95 females & 41 males). The basic principle of ...

Four chronic typhoid carriers from the Aberdeen typhoid outbreak of 1964 were treated with trimethoprim-sulphamethoxazole. The male carrier remained clear of infection following treatment but the three female carriers, all with gall bladder abnormalities, remained excretors. A convalescent typhoid excretor also remained clear of infection after treatment as well as two other salmonella carriers...