Primary cutaneous actinomycosis is a rare clinical form with variable presentation. The tumoral presentation of actinomycosis as pseudocarcinomatous or sarcomatous masses is completely rare. The management of cutaneous actinomycosis needs proper antibiotic treatment and surgical resection would not be adequate alone. Herein, we report a case of primary cutaneous actinomycosis on the dorsal surf...

Tumoral calcinosis is a rare syndrome characterized by massive subcutaneous soft tissue deposits of calcium phosphate near the large joints. It is more prevalent in patients with chronic kidney disease undergoing dialysis. A 57-year-old woman was referred to our pain clinic with the complaint of severe pain in the left buttock and lateral hip. The patient had been suffering from chronic kidney ...

We have read with interest the study of Rubbia-Brandt et al. [1] entitled ‘Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer’. In this study, the investigators identified in the specimens from liver resection for colorectal metastases, some histological lesions of the non-tumoral liver parenchyma attributed to oxal...

This case report presented a simultaneous right colon tumor detected perioperatively in patient who developed ileus due to metastatic left the preoperative period. A seventy-six-year-old man was admitted with epigastric pain, nausea, and vomiting. There tenderness defense on deep palpation epigastrium. On computed tomography, there were multiple hypodense lesions liver, mass at level of splenic...

Purpose To report the clinical and histopathological findings of atypical intravitreal growth of a retinoblastoma with a multi-branching configuration. Observations A 7-month-old boy was referred to our hospital due to leukocoria in the right eye. Ophthalmic examinations identified multi-branching vessels surrounded by diaphanous tissue behind the lens in the right eye. Imaging modalities sho...

Tumoral calcinosis is a rare condition characterized by deposits of calcium hydroxyapatite crystals in periarticular soft tissues. Three clinical settings are possible: complication of renal dialysis, hereditary and sporadic. The condition more commonly affects adults, is rare in children and extremely uncommon in infants. A case of sporadic tumoral calcinosis of the hip is reported in a six-ye...

A 73-years old man was admitted on March 1997, complaining of asthenia, muscle weakness, dry cough, bronchospasm and paresthesis of arms and legs. A WBC count was 13.5 x 109/I with 44% of mature eosinophils. A blood test performed 7 months earlier revealed similar values. The neurological diagnosis was an axonal peripheral polyneuropathy (motor and sensitive). Stool examinations, IgE dosage, CA...

DOI: 10.7247/jiumf.2012.19.1.40_45 Background: Chronic Myelogenous Leukemia (CML) is a myeloproliferative disorder characterized by, overproduction of myeloid cells. Hydroxyurea is an antimetabolite which is commonly used in myeloproliferative syndromes. Reported skin changes related to hydroxyurea therapy may range form xerosis to mucocutaneous cancers. Aim: In this study, our aim was to under...

BACKGROUND Calcinosis cutis is the cutaneous deposition of calcium salts. Tumoral Calcinosis is a condition consisting of massive subcutaneous deposits of calcium salts often overlying large joints in otherwise healthy patients. OBJECTIVE To describe the characteristics of a series of patients with Tumoral Calcinosis in the Gurage Zone of Central Ethiopia. METHODOLOGY Data was collected fro...

Despite significant progress in treatment, chronic lymphocytic leukemia (CLL) remains an incurable disease. Advances have been made to understand the molecular pathogenesis underlying CLL progression and treatment resistance. We here review the available evidences concerning the role of the B-cell receptor (BCR) and the tumor microenvironment interactions in CLL pathogenesis. Antigen likely has...