Abstract Breast cancer is the most common that causes death in women. Conventional therapies, including surgery and chemotherapy, have different therapeutic effects are commonly associated with risks side effects. Near infrared radiation a technique few used for local hyperthermia, typically as an adjuvant to other therapies. The understanding of use near NIR monotherapy, its on immune cells ac...

malignant germ-cell tumors (mgct) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. endodermal sinus tumor (est) forms the most common histologic subtype of mgct. the vagina is an extremely rare site for gcts. an 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. she was pale and a mass was palpable ...

purpose: to recognize affective factors in delivering x-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.   materials and methods: since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). x-ray imaging was done to determine geometric features of liver.   results: radio...

Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Materials and Methods: Twenty-five patients (12 males and 13 females, aged between 8 and...

background: alteration in peripheral blood lymphocytes (pbls) is usually investigated to provide an evidence of the host immune responses to tumor antigens. the tumor infiltrating nk cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. objective: to analyze peripheral blood and tumor associated natural killer (nk) cells in patients with breast ca...

BACKGROUND Tyrosine kinase inhibitors (TKIs) have been used as standard therapy for patients with advanced renal cell carcinoma (RCC). However, information on factors predicting response to treatment with TKIs is lacking. This study aimed to assess the association between initial tumor size, involved organs, pre-treatment C-reactive protein (CRP) levels, and reduction in tumor size in patients ...

the armadillo could be considered as an experimental model for leprosy studies. mycobacterium leprae main host cells are macrophages and schwann cells. however, endocytosis and germicidal activities of armadillo macrophages and monocytes have not yet been evaluated. the aim of this research was to evaluate endocytosis and nbt-reduction activities of monocyte-derived macrophages (mdm) and monocy...

Vinblastine (VLB) previously has been shown to perturb tumor blood flow, but the effect of these perturbations on tissue oxygenation is not known. The recent development of electron paramagnetic resonance (EPR) oximetry now has made it feasible to measure the effects of changes of perfusion on the pO(2) in tumors and normal tissues as a function of time and dose. We measured changes in tumor pe...