persons infected with the human immunodeficiency virus (hiv) are particularly susceptible to tuberculosis, either by latent infection reactivation or by a primary infection with rapid progression to active disease. this study was done to determine the frequency of tuberculosis infection among iranian patients with hiv/aids. a total of 262 hiv/aids patients attending all three hiv/aids health ca...

BACKGROUND The immunologic environment during HIV/M. tuberculosis co-infection is characterized by cytokine and chemokine irregularities that have been shown to increase immune activation, viral replication, and T cell dysfunction. METHODS We analysed ex vivo plasma samples from 17 HIV negative and 16 HIV pulmonary tuberculosis co infected cases using Luminex assay to see impact of HIV co-inf...

AIM To determine association between tuberculosis (TB) related stigma and delay in seeking a treatment after the onset of symptoms associated with tuberculosis. METHODS This prospective study was carried out in the "Podhrastovi" University Clinic of Lung Diseases and Tuberculosis and Health facilities for lung diseases and tuberculosis in the Sarajevo area. The sample consisted of 300 tubercu...

Introduction: Primary tuberculosis (TB) of the oropharynx and nasopharynx is an extremely rare form of extra-pulmonary TB in children. Primary tuberculosis occurs more likely secondary to pulmonary TB and is more common in immunocompromised patients.   Case Report: We reported the case of a young male presented with the symptoms of non-specific chronic adenotonsillitis, ...

• ART-containing integrase inhibitors could be associated with higher incidence of TB-associated IRIS. Prospective studies are needed to better characterize the risk IRIS-TB and determine optimal ART regimen for TB-HIV coinfected patients. Tuberculosis is a immune reconstitution inflammatory syndrome (IRIS) after initiation. Data from all patients newly diagnosed tuberculosis disease uncontroll...

AIMS Use of the polymerase chain reaction for the detection of Mycobacterium tuberculosis (TB PCR) as a basis for making clinical decisions on the initiation of antituberculosis treatment was studied. METHODS A retrospective study involving a cohort of 155 patients being investigated for tuberculosis in an infectious disease consultation service was undertaken. TB PCR was performed on pulmona...

results cox regression analysis showed that co-infection with hiv significantly affects the survival rate of tb patients so that the rate of death was 20.7 (8.1-53) times more than tb infected patients alone. also, married patients with tuberculosis were 2.7 times more at risk of death than single subjects. we also confirmed that in hiv/tb positive patients, married individuals were more prone ...

Background: At present, despite the generally favorable pathomorphosis of tuberculosis (TB), a number factors that have negative impact on epidemiological situation, clinical manifestations and treatment outcomes remain. Objective: To determine role aggravating in development destructive pulmonary tuberculosis. Material methods: A prospective cohort study was conducted. The patients who were ad...

introduction and objectives: tuberculosis (tb) still remains a major health concern both in developing and developed countries. the rate of the liver injury due to anti-tb drugs in developed countries has been reported up to 4%. the goal of this study is to assess the rate and risk factors for anti-tuberculosis drug-induced liver injury (dili). also, a model has been designed to predict dili in...