We have examined the effect of a synthetic low-molecular-weight ma trix metalloproteinase inhibitor, [4-(A'-hydroxyamino)-2/?-isobutyl-3S(thiopen-2-ylthiomethyl)-succinyl]-i.-phenylalanine-iV-methylamide (BB94), on human ovarian carcinoma xenografts growing in nude mice. The xenografts grew as thick intraperitoneal mucinous ascites containing freefloating tumor cell clumps. The ascites increase...

Per-pixel classification algorithms are poorly equipped to monitor urban land use i n images acquired by the current generation of high spatial resolution satellite sensors. This is because urban areas commonly comprise a complex spatial assemblage of spectrally distinct land-cover types. In this study, a technique is described that attempts to derive information on urban land use in two stages...

Ž . We present the first computation of the thermodynamic properties of the complex su 3 Toda theory. This is possible thanks to a new string hypothesis, which involves bound states that are non-self-conjugate solutions of the Bethe equations. Ž . Our method provides equivalently the solution of the su 3 generalization of the XXZ chain. In the repulsive regime, we confirm that the scattering th...

As part of an intensive study of crop response to CO 2 enrichment in a free-air CO2 enrichment (FACE) experiment in the field, we determined aspects of the water relations of a cotton crop on selected dates in 1991. The atmosphere was enriched from 370 #mol CO2 mo1-1 (control) to about 550 #mol mo1-1 in free air during daylight hours. Under full irrigation, CO2 enrichment decreased stomatal con...

We describe a DBpedia extractor materializing the editing history of Wikipedia pages as linked data to support queries and indicators on the history. The different instances of the DBpedia platform typically extract RDF from Wikipedia using up to 16 extractors. The extraction focuses on structured content including infoboxes, categories, links, etc. As an example, the French chapter, of which w...

The organization of actin and myosin in vascular endothelial cells in situ was studied by immunofluorescence microscopy. Examination of perfusion-fixed, whole mounts of normal mouse and rat descending thoracic aorta revealed the presence of axially oriented stress fibers containing both actin and myosin within the endothelial cells. In both species, the proportion of cells containing stress fib...

Hedgehog (Hh) proteins belong to a class of morphogens involved in many biological processes during embry-onic development; they are relatively silent during normal adult life although they may be recruited postnatally in re-sponse to tissue injury. Three secreted proteins have been identified: Sonic hedgehog (Shh), Desert hedgehog and Indianhedgehog. The interaction of Hh ligand wi...