BACKGROUND/AIMS Sequential therapy is one of the recent answers given to the problem of increasing antibiotic resistance and decreasing eradication rates of Helicobacter pylori infection. The aim of this study is to compare the ornidazole-based sequentialtherapy with the standard triple therapy in Helicobacter pylori eradication. MATERIALS AND METHODS Children aged 4-18 years diagnosed with H...

The aim of this study was to delineate the clinical and therapeutic characteristics of Pseudomonas aeruginosa bronchopulmonary infection in acquired immunodeficiency syndrome (AIDS) patients. Eighteen AIDS patients had 39 episodes of P. aeruginosa bronchopulmonary infection. Their mean CD4 cell count was 0.012+/-0.011 cells x 10(9) x L(-1) and two episodes (5.1%) occurred in neutropenic patient...

BACKGROUND Helicobacter pylori eradication fails in about 10% of patients, particularly because of the occurrence of resistance to antibiotics and side-effects. During anti-H. pylori therapy, probiotics have been successfully used to reduce the incidence of side-effects. AIM To evaluate the effect of Bacillus clausii, a probiotic, on incidence (primary variable) and severity of antibiotic-ass...

We investigated the effects of triple antibiotic paste (TAP) and modified triple antibiotic paste (MTAP) concentrations on the microhardness and chemical structure of radicular dentine. Human root cylinders were instrumented and randomized into four treatment groups and an untreated control group. Two treatment groups received 1 g/mL TAP or MTAP, and the other two treatment groups received 1 mg...

Isolation of Pasteurella multocida was attempted from the heart blood, spleen, liver and lung collected from turkeys (4 No,s) and chicken (4 No,s) suspected to have died of avian pasteurellosis. A total of eight P. multocida isolates were isolated and identified on the basis of biochemical characteristics, pathogenicity studies in mice and PM-PCR. The In vitro antibiotic sensitivity test of the...

In a controlled trial of rosoxacin in patients with non-gonococcal urethritis (NGU), 150 mg of the antibiotic given twice daily for 10 days was compared with 300 mg triple tetracycline (Deteclo) given twice daily for the same period. Only six (19%) of 31 patients treated with rosoxacin were free of urethritis after 10 days; Chlamydia trachomatis was reisolated from 12 (92%) of 13 patients who w...

Helicobacter pylori (H pylori) is a common chronic bacterial infection that is an important cause of peptic ulcer disease and gastroduodenal disease in children. H pylori is also associated with extragastric manifestations, including growth reduction, iron-deficiency anemia, and idiopathic thrombocytopenic purpura. Current guidelines recommend endoscopy with biopsy for the definitive demonstrat...

Since antibiotic resistance usually affords a gain of function, there is an associated biological cost resulting in a loss of fitness of the bacterial host. Considering that antibiotic resistance is most often only transiently advantageous to bacteria, an efficient and elegant way for them to escape the lethal action of drugs is the alteration of resistance gene expression. It appears that expr...

We describe a challenging case of patient with metallo-beta-lactamase-producing Pseudomonas aeruginosa sternal osteomyelitis following aortic valve replacement biological prosthesis. The strain exhibited multidrug-resistance phenotype carrying the blaVIM-1 gene and belonged to high-risk clone sequence type ST235. was successfully treated surgical debridement plus antibiotic therapy ceftazidime/...

AIM: The aim of this study is to evaluate the antimicrobial effect pre-synthesized novel antibiotic loaded electrospun nanofibers and compare it with conventional triple paste when used in patients immature necrotic teeth. METHODS: Antibiotic were fabricated by electrospinning. Thirty-four teeth included study. In first visit, access cavity preparation was performed obtain bacteriological sampl...